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Cinaciguat (BAY-582667) Modifies Cardiopulmonary and Systemic Circulation in Chronically Hypoxic and Pulmonary Hypertensive Neonatal Lambs in the Alto Andino

Neonatal pulmonary hypertension (NPHT) is produced by sustained pulmonary vasoconstriction and increased vascular remodeling. Soluble guanylyl cyclase (sGC) participates in signaling pathways that induce vascular vasodilation and reduce vascular remodeling. However, when sGC is oxidized and/or loses...

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Detalles Bibliográficos
Autores principales:	Beñaldo, Felipe A., Araya-Quijada, Claudio, Ebensperger, Germán, Herrera, Emilio A., Reyes, Roberto V., Moraga, Fernando A., Riquelme, Alexander, Gónzalez-Candia, Alejandro, Castillo-Galán, Sebastián, Valenzuela, Guillermo J., Serón-Ferré, María, Llanos, Aníbal J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9207417/ https://www.ncbi.nlm.nih.gov/pubmed/35733986 http://dx.doi.org/10.3389/fphys.2022.864010

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