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Metformin Induces PRODH/POX-Dependent Apoptosis in Breast Cancer Cells

Although the antineoplastic activity of metformin (MET) is well established, the underlying mechanism of the activity is not understood. Since MET activates AMP kinase (AMPK) and proline dehydrogenase/proline oxidase (PRODH/POX) is stimulated by AMPK ligands (implicated in the regulation of cancer c...

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Detalles Bibliográficos
Autores principales:	Huynh, Thi Yen Ly, Oscilowska, Ilona, Szoka, Lukasz, Piktel, Ewelina, Baszanowska, Weronika, Bielawska, Katarzyna, Bucki, Robert, Miltyk, Wojciech, Palka, Jerzy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9207455/ https://www.ncbi.nlm.nih.gov/pubmed/35733940 http://dx.doi.org/10.3389/fmolb.2022.869413

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