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Low-dose interleukin-2 reverses chronic migraine-related sensitizations through peripheral interleukin-10 and transforming growth factor beta-1 signaling

Low-dose interleukin-2 (LD-IL-2) treatment has been shown to effectively reverse chronic migraine-related behaviors and the sensitization of trigeminal ganglion (TG) neurons through expansion and activation of peripheral regulatory T cells (Tregs) in mice. In this study, we investigated the molecula...

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Detalles Bibliográficos
Autores principales:	Guo, Zhaohua, Zhang, Jintao, Liu, Xuemei, Unsinger, Jacqueline, Hotchkiss, Richard S, Cao, Yu-Qing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9207571/ https://www.ncbi.nlm.nih.gov/pubmed/35733705 http://dx.doi.org/10.1016/j.ynpai.2022.100096

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