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A unified statistical potential reveals that amino acid stickiness governs nonspecific recruitment of client proteins into condensates
Membraneless organelles are cellular compartments that form by liquid–liquid phase separation of one or more components. Other molecules, such as proteins and nucleic acids, will distribute between the cytoplasm and the liquid compartment in accordance with the thermodynamic drive to lower the free...
Autores principales: | Villegas, José A., Levy, Emmanuel D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9207749/ https://www.ncbi.nlm.nih.gov/pubmed/35762716 http://dx.doi.org/10.1002/pro.4361 |
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