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Sulfavant A as the first synthetic TREM2 ligand discloses a homeostatic response of dendritic cells after receptor engagement

OBJECTIVE: The immune response arises from a fine balance of mechanisms that provide for surveillance, tolerance, and elimination of dangers. Sulfavant A (SULF A) is a sulfolipid with a promising adjuvant activity. Here we studied the mechanism of action of SULF A and addressed the identification of...

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Detalles Bibliográficos
Autores principales: Gallo, Carmela, Manzo, Emiliano, Barra, Giusi, Fioretto, Laura, Ziaco, Marcello, Nuzzo, Genoveffa, d’Ippolito, Giuliana, Ferrera, Francesca, Contini, Paola, Castiglia, Daniela, Angelini, Claudia, De Palma, Raffaele, Fontana, Angelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9207826/
https://www.ncbi.nlm.nih.gov/pubmed/35723745
http://dx.doi.org/10.1007/s00018-022-04297-z

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