Targeting protein–protein interaction for immunomodulation: A sunflower trypsin inhibitor analog peptidomimetic suppresses RA progression in CIA model

Protein–protein interactions (PPI) of co-stimulatory molecules CD2-CD58 are important in the early stage of an immune response, and increased expression of these co-stimulatory molecules is observed in the synovial region of joints in rheumatoid arthritis (RA) patients. A CD2 epitope region that bin...

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Detalles Bibliográficos
Autores principales: Dahal, Achyut, Parajuli, Pravin, Singh, Sitanshu S., Shrestha, Leeza, Sonju, Jafrin Jobayer, Shrestha, Prajesh, Chatzistamou, Ioulia, Jois, Seetharama
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9208026/
https://www.ncbi.nlm.nih.gov/pubmed/35641025
http://dx.doi.org/10.1016/j.jphs.2022.04.005

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