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The genomic landscape of metastatic clear cell renal cell carcinoma after systemic therapy
Primary clear cell renal cell carcinoma (ccRCC) has been previously characterized, but the genomic landscape of metastatic ccRCC is largely unexplored. Here, we performed whole exome sequencing (WES) in 68 samples from 44 patients with ccRCC, including 52 samples from a metastatic site. SETD2, PBRM1...
Autores principales: | van der Mijn, Johannes C., Eng, Kenneth W., Chandra, Pooja, Fernandez, Evan, Ramazanoglu, Sinan, Sigaras, Alexandros, Oromendia, Clara, Gudas, Lorraine J., Tagawa, Scott T., Nanus, David M., Faltas, Bishoy F., Beltran, Himisha, Sternberg, Cora N., Elemento, Olivier, Sboner, Andrea, Mosquera, Juan Miguel, Molina, Ana M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9208073/ https://www.ncbi.nlm.nih.gov/pubmed/35231161 http://dx.doi.org/10.1002/1878-0261.13204 |
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