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TGFβ selects for pro‐stemness over pro‐invasive phenotypes during cancer cell epithelial–mesenchymal transition

Transforming growth factor β (TGFβ) induces epithelial–mesenchymal transition (EMT), which correlates with stemness and invasiveness. Mesenchymal–epithelial transition (MET) is induced by TGFβ withdrawal and correlates with metastatic colonization. Whether TGFβ promotes stemness and invasiveness sim...

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Detalles Bibliográficos
Autores principales: Tsubakihara, Yutaro, Ohata, Yae, Okita, Yukari, Younis, Shady, Eriksson, Jens, Sellin, Mikael E., Ren, Jiang, ten Dijke, Peter, Miyazono, Kohei, Hikita, Atsuhiko, Imamura, Takeshi, Kato, Mitsuyasu, Heldin, Carl‐Henrik, Moustakas, Aristidis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9208077/
https://www.ncbi.nlm.nih.gov/pubmed/35348275
http://dx.doi.org/10.1002/1878-0261.13215