Cargando…

TGFβ selects for pro‐stemness over pro‐invasive phenotypes during cancer cell epithelial–mesenchymal transition

Transforming growth factor β (TGFβ) induces epithelial–mesenchymal transition (EMT), which correlates with stemness and invasiveness. Mesenchymal–epithelial transition (MET) is induced by TGFβ withdrawal and correlates with metastatic colonization. Whether TGFβ promotes stemness and invasiveness sim...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tsubakihara, Yutaro, Ohata, Yae, Okita, Yukari, Younis, Shady, Eriksson, Jens, Sellin, Mikael E., Ren, Jiang, ten Dijke, Peter, Miyazono, Kohei, Hikita, Atsuhiko, Imamura, Takeshi, Kato, Mitsuyasu, Heldin, Carl‐Henrik, Moustakas, Aristidis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9208077/ https://www.ncbi.nlm.nih.gov/pubmed/35348275 http://dx.doi.org/10.1002/1878-0261.13215

Ejemplares similares

TGFβ and EGF signaling orchestrates the AP-1- and p63 transcriptional regulation of breast cancer invasiveness
por: Sundqvist, Anders, et al.
Publicado: (2020)

LXRα limits TGFβ-dependent hepatocellular carcinoma associated fibroblast differentiation
por: Morén, Anita, et al.
Publicado: (2019)

Epithelial-Mesenchymal Transition and Metastasis under the Control of Transforming Growth Factor β
por: Tsubakihara, Yutaro, et al.
Publicado: (2018)

The TGFB2-AS1 lncRNA Regulates TGF-β Signaling by Modulating Corepressor Activity
por: Papoutsoglou, Panagiotis, et al.
Publicado: (2019)

Regulation of Bone Morphogenetic Protein Signaling by ADP-ribosylation
por: Watanabe, Yukihide, et al.
Publicado: (2016)

Mechanisms of TGFβ-Induced Epithelial–Mesenchymal Transition
por: Moustakas, Aristidis, et al.
Publicado: (2016)

BMP signaling is a therapeutic target in ovarian cancer
por: Fukuda, Tomohiko, et al.
Publicado: (2020)

Negative Regulation of TGFβ Signaling by the Kinase LKB1 and the Scaffolding Protein LIP1
por: Morén, Anita, et al.
Publicado: (2011)

Notch signaling is necessary for epithelial growth arrest by TGF-β
por: Niimi, Hideki, et al.
Publicado: (2007)

JUNB governs a feed-forward network of TGFβ signaling that aggravates breast cancer invasion
por: Sundqvist, Anders, et al.
Publicado: (2018)

Emergence, development and diversification of the TGF-β signalling pathway within the animal kingdom
por: Huminiecki, Lukasz, et al.
Publicado: (2009)

TGFβ induces SIK to negatively regulate type I receptor kinase signaling
por: Kowanetz, Marcin, et al.
Publicado: (2008)

Transforming growth factor β (TGFβ) induces NUAK kinase expression to fine-tune its signaling output
por: Kolliopoulos, Constantinos, et al.
Publicado: (2019)

JNK-Dependent cJun Phosphorylation Mitigates TGFβ- and EGF-Induced Pre-Malignant Breast Cancer Cell Invasion by Suppressing AP-1-Mediated Transcriptional Responses
por: Sundqvist, Anders, et al.
Publicado: (2019)

Genome–wide binding of transcription factor ZEB1 in triple‐negative breast cancer cells
por: Maturi, Varun, et al.
Publicado: (2018)

Serglycin activates pro-tumorigenic signaling and controls glioblastoma cell stemness, differentiation and invasive potential
por: Manou, Dimitra, et al.
Publicado: (2020)

Bone morphogenetic protein type IB receptor is progressively expressed in malignant glioma tumours.
por: Yamada, N., et al.
Publicado: (1996)

Snail mediates crosstalk between TGFβ and LXRα in hepatocellular carcinoma
por: Bellomo, Claudia, et al.
Publicado: (2017)

The polarity protein Par3 coordinates positively self-renewal and negatively invasiveness in glioblastoma
por: Dadras, Mahsa Shahidi, et al.
Publicado: (2021)

Pro-invasive properties of Snail1 are regulated by sumoylation in response to TGFβ stimulation in cancer
por: Gudey, Shyam Kumar, et al.
Publicado: (2017)

Genomewide binding of transcription factor Snail1 in triple‐negative breast cancer cells
por: Maturi, Varun, et al.
Publicado: (2018)

Cell-surface GPNMB and induction of stemness
por: Okita, Yukari, et al.
Publicado: (2018)

Loss of SNAI1 induces cellular plasticity in invasive triple-negative breast cancer cells
por: Tsirigoti, Chrysoula, et al.
Publicado: (2022)

Extracellular Fibrillar Structure of Latent TGFβ Binding Protein-1: Role in TGFβ-dependent Endothelial-Mesenchymal Transformation during Endocardial Cushion Tissue Formation in Mouse Embryonic Heart
por: Nakajima, Yuji, et al.
Publicado: (1997)

The long non-coding RNA LINC00707 interacts with Smad proteins to regulate TGFβ signaling and cancer cell invasion
por: Gélabert, Caroline, et al.
Publicado: (2023)

TGF-β Signaling
por: Tzavlaki, Kalliopi, et al.
Publicado: (2020)

Transforming growth factor-β employs HMGA2 to elicit epithelial–mesenchymal transition
por: Thuault, Sylvie, et al.
Publicado: (2006)

The Major RNA-Binding Protein ProQ Impacts Virulence Gene Expression in Salmonella enterica Serovar Typhimurium
por: Westermann, Alexander J., et al.
Publicado: (2019)

Tumor Promoting Effect of BMP Signaling in Endometrial Cancer
por: Fukuda, Tomohiko, et al.
Publicado: (2021)

The high mobility group A2 protein epigenetically silences the Cdh1 gene during epithelial-to-mesenchymal transition
por: Tan, E-Jean, et al.
Publicado: (2015)

Extracellular Vesicles and Transforming Growth Factor β Signaling in Cancer
por: Rodrigues-Junior, Dorival Mendes, et al.
Publicado: (2022)

Long non‐coding RNAs and TGF‐β signaling in cancer
por: Papoutsoglou, Panagiotis, et al.
Publicado: (2020)

Smad7 and protein phosphatase 1α are critical determinants in the duration of TGF-β/ALK1 signaling in endothelial cells
por: Valdimarsdottir, Gudrun, et al.
Publicado: (2006)

Transforming Growth Factor β Promotes Complexes between Smad Proteins and the CCCTC-binding Factor on the H19 Imprinting Control Region Chromatin
por: Bergström, Rosita, et al.
Publicado: (2010)

Nucleosome regulatory dynamics in response to TGFβ
por: Enroth, Stefan, et al.
Publicado: (2014)

p53: Pro-aging or pro-longevity?
por: de Keizer*, Peter L.J., et al.
Publicado: (2010)

Pro Tools 8: Pro Tools for film and video
por: Angell, Dale
Publicado: (2009)

The role of pyroptosis in cancer: pro-cancer or pro-“host”?
por: Xia, Xiaojing, et al.
Publicado: (2019)

Facebook as a Pro-Ana and Pro-Mia resource
por: Jordan, G. Lladó, et al.
Publicado: (2021)

Instagram, the new ally of Pro-Ana and Pro-Mia
por: Jordan, G. Lladó, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_j0ki1jmik1lf9j73v6r268qea6