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TGFβ selects for pro‐stemness over pro‐invasive phenotypes during cancer cell epithelial–mesenchymal transition
Transforming growth factor β (TGFβ) induces epithelial–mesenchymal transition (EMT), which correlates with stemness and invasiveness. Mesenchymal–epithelial transition (MET) is induced by TGFβ withdrawal and correlates with metastatic colonization. Whether TGFβ promotes stemness and invasiveness sim...
Autores principales: | Tsubakihara, Yutaro, Ohata, Yae, Okita, Yukari, Younis, Shady, Eriksson, Jens, Sellin, Mikael E., Ren, Jiang, ten Dijke, Peter, Miyazono, Kohei, Hikita, Atsuhiko, Imamura, Takeshi, Kato, Mitsuyasu, Heldin, Carl‐Henrik, Moustakas, Aristidis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9208077/ https://www.ncbi.nlm.nih.gov/pubmed/35348275 http://dx.doi.org/10.1002/1878-0261.13215 |
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