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On clustering for cell-phenotyping in multiplex immunohistochemistry (mIHC) and multiplexed ion beam imaging (MIBI) data

OBJECTIVE: Multiplex immunohistochemistry (mIHC) and multiplexed ion beam imaging (MIBI) images are usually phenotyped using a manual thresholding process. The thresholding is prone to biases, especially when examining multiple images with high cellularity. RESULTS: Unsupervised cell-phenotyping met...

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Detalles Bibliográficos
Autores principales: Seal, Souvik, Wrobel, Julia, Johnson, Amber M., Nemenoff, Raphael A., Schenk, Erin L., Bitler, Benjamin G., Jordan, Kimberly R., Ghosh, Debashis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9208090/
https://www.ncbi.nlm.nih.gov/pubmed/35725622
http://dx.doi.org/10.1186/s13104-022-06097-x