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On clustering for cell-phenotyping in multiplex immunohistochemistry (mIHC) and multiplexed ion beam imaging (MIBI) data
OBJECTIVE: Multiplex immunohistochemistry (mIHC) and multiplexed ion beam imaging (MIBI) images are usually phenotyped using a manual thresholding process. The thresholding is prone to biases, especially when examining multiple images with high cellularity. RESULTS: Unsupervised cell-phenotyping met...
Autores principales: | Seal, Souvik, Wrobel, Julia, Johnson, Amber M., Nemenoff, Raphael A., Schenk, Erin L., Bitler, Benjamin G., Jordan, Kimberly R., Ghosh, Debashis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9208090/ https://www.ncbi.nlm.nih.gov/pubmed/35725622 http://dx.doi.org/10.1186/s13104-022-06097-x |
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