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A Japanese case of castration-resistant prostate cancer with BRCA2 and RB1 co-loss and TP53 mutation: a case report

BACKGROUND: Abnormalities in homologous recombination contribute to the aggressive nature of castration-resistant prostate cancer. Retinoblastoma transcriptional corepressor 1 (RB1) and breast cancer 2 (BRCA2) exist close to each other in the same chromosome, and the significance of their concurrent...

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Detalles Bibliográficos
Autores principales:	Iwasawa, Tomohiro, Kosaka, Takeo, Morita, Shinya, Mikami, Shuji, Nakamura, Kohei, Hongo, Hiroshi, Nishihara, Hiroshi, Oya, Mototsugu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9208097/ https://www.ncbi.nlm.nih.gov/pubmed/35725469 http://dx.doi.org/10.1186/s12920-022-01286-w

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