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HLA-E restricted cytomegalovirus UL40 peptide polymorphism may represent a risk factor following congenital infection

BACKGROUND: Congenital cytomegalovirus immunopathogenesis is largely unknown and multifactorial due to the complex interactions between viral, maternal, placental, and child factors. Polymorphisms in the HLA-E binding UL40(15-23) peptide mimics HLA-E complexed peptides from certain HLA-A, -B, -C and...

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Detalles Bibliográficos
Autores principales: Tarragó, David, González, Irene, González-Escribano, Maria Francisca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9208114/
https://www.ncbi.nlm.nih.gov/pubmed/35725386
http://dx.doi.org/10.1186/s12864-022-08689-0

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