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Need for optimized dosages in the design of comparative clinical trials of anti-malarial drugs

We read with interest the publication on malaria treatment by Obonyo et al. (Malaria J 21:30, 2022). This commentary questions the methodology, especially the chosen time points of treatment outcome measures.

Detalles Bibliográficos
Autores principales: Krishna, Sanjeev, Kremsner, Peter G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9208120/
https://www.ncbi.nlm.nih.gov/pubmed/35725411
http://dx.doi.org/10.1186/s12936-022-04170-1
Descripción
Sumario:We read with interest the publication on malaria treatment by Obonyo et al. (Malaria J 21:30, 2022). This commentary questions the methodology, especially the chosen time points of treatment outcome measures.