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Apelin alleviated neuroinflammation and promoted endogenous neural stem cell proliferation and differentiation after spinal cord injury in rats

BACKGROUND: Spinal cord injury (SCI) causes devastating neurological damage, including secondary injuries dominated by neuroinflammation. The role of Apelin, an endogenous ligand that binds the G protein-coupled receptor angiotensin-like receptor 1, in SCI remains unclear. Thus, our aim was to inves...

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Detalles Bibliográficos
Autores principales: Liu, Qing, Zhou, Shuai, Wang, Xiao, Gu, Chengxu, Guo, Qixuan, Li, Xikai, Zhang, Chunlei, Zhang, Naili, Zhang, Luping, Huang, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9208139/
https://www.ncbi.nlm.nih.gov/pubmed/35725619
http://dx.doi.org/10.1186/s12974-022-02518-7

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