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Complement C3a activates astrocytes to promote medulloblastoma progression through TNF-α

BACKGROUND: Medulloblastoma (MB) is the most common malignant brain tumor in children. Approximately one-third of MB patients remain incurable. Understanding the molecular mechanism of MB tumorigenesis is, therefore, critical for developing specific and effective treatment strategies. Our previous w...

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Detalles Bibliográficos
Autores principales: Gong, Biao, Guo, Duancheng, Zheng, Chaonan, Ma, Zhen, Zhang, Jie, Qu, Yanghui, Li, Xinhua, Li, Gen, Zhang, Li, Wang, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9208237/
https://www.ncbi.nlm.nih.gov/pubmed/35725556
http://dx.doi.org/10.1186/s12974-022-02516-9

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