The Type I Interferon Pathway Is Upregulated in the Cutaneous Lesions and Blood of Multibacillary Leprosy Patients With Erythema Nodosum Leprosum

In leprosy patients, acute inflammatory episodes, known as erythema nodosum leprosum (ENL), are responsible for high morbidity and tissue damage that occur during the course of Mycobacterium leprae infection. In a previous study, we showed evidence implicating DNA-sensing via TLR9 as an important in...

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Detalles Bibliográficos
Autores principales: Rosa, Thabatta Leal Silveira Andrezo, Mendes, Mayara Abud, Linhares, Natasha Ribeiro Cardoso, Rodrigues, Thais Fernanda, Dias, André Alves, Leal-Calvo, Thyago, Gandini, Mariana, Ferreira, Helen, Costa, Fabrício da Mota Ramalho, Sales, Anna Maria, Amadeu, Thaís Porto, Schmitz, Veronica, Pinheiro, Roberta Olmo, Rodrigues, Luciana Silva, Moraes, Milton Ozório, Pessolani, Maria Cristina Vidal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9208291/
https://www.ncbi.nlm.nih.gov/pubmed/35733868
http://dx.doi.org/10.3389/fmed.2022.899998

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