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JAK1/2 Inhibitor Baricitinib Improves Skin Fibrosis and Digital Ulcers in Systemic Sclerosis

BACKGROUND: Systemic sclerosis (SSc) is a rare disabling connective tissue disease with few available treatment options. Diffuse cutaneous systemic sclerosis (dcSSc) is associated with high mortality. A previous experiment has shown that JAK2 inhibitor can significantly improve skin fibrosis in bleo...

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Detalles Bibliográficos
Autores principales:	Hou, Zhanying, Su, Xuehan, Han, Guangming, Xue, Ruzeng, Chen, Yangxia, Chen, Ye, Wang, Huan, Yang, Bin, Liang, Yunsheng, Ji, Suyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9208297/ https://www.ncbi.nlm.nih.gov/pubmed/35733864 http://dx.doi.org/10.3389/fmed.2022.859330

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