Cargando…
Inhibiting C-4 Methyl Sterol Oxidase with Novel Diazaborines to Target Fungal Plant Pathogens
[Image: see text] With resistance to current agricultural fungicides rising, a great need has emerged for new antifungals with unexploited targets. In response, we report a novel series of diazaborines with potent activity against representative fungal plant pathogens. To identify their mode of acti...
Autores principales: | Kim, Sang Hu, Steere, Luke, Zhang, Yong-Kang, McGregor, Cari, Hahne, Chris, Zhou, Yasheen, Liu, Chunliang, Cai, Yan, Zhou, Haibo, Chen, Xuefei, Puumala, Emily, Duncan, Dustin, Wright, Gerard D., Liu, C. Tony, Whitesell, Luke, Cowen, Leah E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9208374/ https://www.ncbi.nlm.nih.gov/pubmed/35584803 http://dx.doi.org/10.1021/acschembio.2c00257 |
Ejemplares similares
-
Multifactor transcriptional control of alternative oxidase induction integrates diverse environmental inputs to enable fungal virulence
por: Liu, Zhongle, et al.
Publicado: (2023) -
The Trisubstituted Isoxazole MMV688766 Exerts Broad-Spectrum Activity against Drug-Resistant Fungal Pathogens through Inhibition of Lipid Homeostasis
por: Puumala, Emily, et al.
Publicado: (2022) -
Diazaborines as New Inhibitors of Human Neutrophil
Elastase
por: António, João P. M., et al.
Publicado: (2018) -
Calcineurin Inhibitors Synergize with Manogepix to Kill Diverse Human Fungal Pathogens
por: Liston, Sean D., et al.
Publicado: (2022) -
Structural basis for inhibition of the AAA-ATPase Drg1 by diazaborine
por: Prattes, Michael, et al.
Publicado: (2021)