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GDC-0941 activates integrin linked kinase (ILK) expression to cause resistance to GDC-0941 in breast cancer by the tumor necrosis factor (TNF)-α signaling pathway

Breast cancer is characterized by high morbidity and mortality. GDC-0941 is a PI3K inhibitor with oncogenic effects in breast cancer. However, certain breast cancer cells are insensitive to GDC-0941. Hence, the mechanism of GDC-0941 in breast cancer resistance was investigated in this study. Breast...

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Detalles Bibliográficos
Autores principales:	Chen, Haifeng, Cheng, Mingming, Gao, Pengcheng, Zhang, Xiangzhong, Li, Ganggang, Wang, Liting, Qin, Long, Li, Hongrui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9208486/ https://www.ncbi.nlm.nih.gov/pubmed/35477364 http://dx.doi.org/10.1080/21655979.2022.2066758

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