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Shikonin induces apoptosis and autophagy via downregulation of pyrroline-5-carboxylate reductase1 in hepatocellular carcinoma cells

Shikonin(SK) is a natural small molecule naphthoquinone compound, which has anti-cancer activity in various human malignant tumors. Pyrroline-5-carboxylate reductase 1(PYCR1) is involved in tumorigenesis and regulates various cellular processes, including growth, invasion, migration, and apoptosis....

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Detalles Bibliográficos
Autores principales:	Zhang, Junli, Shang, Ling, Jiang, Wendi, Wu, Wenjuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9208523/ https://www.ncbi.nlm.nih.gov/pubmed/35293266 http://dx.doi.org/10.1080/21655979.2022.2052673

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