Accurate Evaluation of Hepatocyte Metabolisms on a Noble Oxygen-Permeable Material With Low Sorption Characteristics

In the pharmaceutical industry, primary cultured hepatocytes is a standard tool used to assess hepatic metabolisms and toxicity in vitro. Drawbacks, however, include their functional deterioration upon isolation, mostly due to the lack of a physiological environment. Polydimethylsiloxane (PDMS) has...

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Detalles Bibliográficos
Autores principales: Nishikawa, Masaki, Ito, Hiroyasu, Tokito, Fumiya, Hirono, Keita, Inamura, Kousuke, Scheidecker, Benedikt, Danoy, Mathieu, Kawanishi, Takumi, Arakawa, Hirohsi, Kato, Yukio, Esashika, Katsuhiro, Miyasako, Hiroshi, Sakai, Yasuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Toxicology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9208656/
https://www.ncbi.nlm.nih.gov/pubmed/35733832
http://dx.doi.org/10.3389/ftox.2022.810478

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