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Successful Treatment of Wound Dehiscence by Innovative Type 1 Collagen Flowable Gel: A Case Report

The growing demand for postbariatric body-contouring surgery after massive weight loss goes hand-in-hand with an increase in wound complications. Consequently, surgical reoperation or conservative management is necessary and represents a difficult challenge to healthcare professionals. Moreover, it...

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Autores principales: Ferraro, Giuseppe A., Lanzano, Giuseppe, Grella, Elisa, Gubitosi, Adelmo, Nicoletti, Giovanni F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9208871/
https://www.ncbi.nlm.nih.gov/pubmed/35747261
http://dx.doi.org/10.1097/GOX.0000000000004360
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author Ferraro, Giuseppe A.
Lanzano, Giuseppe
Grella, Elisa
Gubitosi, Adelmo
Nicoletti, Giovanni F.
author_facet Ferraro, Giuseppe A.
Lanzano, Giuseppe
Grella, Elisa
Gubitosi, Adelmo
Nicoletti, Giovanni F.
author_sort Ferraro, Giuseppe A.
collection PubMed
description The growing demand for postbariatric body-contouring surgery after massive weight loss goes hand-in-hand with an increase in wound complications. Consequently, surgical reoperation or conservative management is necessary and represents a difficult challenge to healthcare professionals. Moreover, it is well known that postbariatric patients present aberrant wound healing due to multifactorial causes, such as preoperative illness, nutritional deficiencies, and vascular disease. To treat such complex wounds, several methods have been recommended, such as the use of negative pressure wound therapy, tissue-engineered skin substitutes, and collagen-based wound dressings. The case presented here is of a patient with deep wound dehiscence of the inner left thigh, 1 week after a medial thigh lift procedure, successfully managed with Vergenix Flowable Gel, a human recombinant type I collagen produced in plants. After 2 weeks of treatment, wound dehiscence was replaced with granulation tissue, and after 4 weeks, the patient was completely healed, with an acceptable aesthetic outcome of the surgical scar.
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spelling pubmed-92088712022-06-22 Successful Treatment of Wound Dehiscence by Innovative Type 1 Collagen Flowable Gel: A Case Report Ferraro, Giuseppe A. Lanzano, Giuseppe Grella, Elisa Gubitosi, Adelmo Nicoletti, Giovanni F. Plast Reconstr Surg Glob Open Reconstructive The growing demand for postbariatric body-contouring surgery after massive weight loss goes hand-in-hand with an increase in wound complications. Consequently, surgical reoperation or conservative management is necessary and represents a difficult challenge to healthcare professionals. Moreover, it is well known that postbariatric patients present aberrant wound healing due to multifactorial causes, such as preoperative illness, nutritional deficiencies, and vascular disease. To treat such complex wounds, several methods have been recommended, such as the use of negative pressure wound therapy, tissue-engineered skin substitutes, and collagen-based wound dressings. The case presented here is of a patient with deep wound dehiscence of the inner left thigh, 1 week after a medial thigh lift procedure, successfully managed with Vergenix Flowable Gel, a human recombinant type I collagen produced in plants. After 2 weeks of treatment, wound dehiscence was replaced with granulation tissue, and after 4 weeks, the patient was completely healed, with an acceptable aesthetic outcome of the surgical scar. Lippincott Williams & Wilkins 2022-06-20 /pmc/articles/PMC9208871/ /pubmed/35747261 http://dx.doi.org/10.1097/GOX.0000000000004360 Text en Copyright © 2022 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of The American Society of Plastic Surgeons. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Reconstructive
Ferraro, Giuseppe A.
Lanzano, Giuseppe
Grella, Elisa
Gubitosi, Adelmo
Nicoletti, Giovanni F.
Successful Treatment of Wound Dehiscence by Innovative Type 1 Collagen Flowable Gel: A Case Report
title Successful Treatment of Wound Dehiscence by Innovative Type 1 Collagen Flowable Gel: A Case Report
title_full Successful Treatment of Wound Dehiscence by Innovative Type 1 Collagen Flowable Gel: A Case Report
title_fullStr Successful Treatment of Wound Dehiscence by Innovative Type 1 Collagen Flowable Gel: A Case Report
title_full_unstemmed Successful Treatment of Wound Dehiscence by Innovative Type 1 Collagen Flowable Gel: A Case Report
title_short Successful Treatment of Wound Dehiscence by Innovative Type 1 Collagen Flowable Gel: A Case Report
title_sort successful treatment of wound dehiscence by innovative type 1 collagen flowable gel: a case report
topic Reconstructive
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9208871/
https://www.ncbi.nlm.nih.gov/pubmed/35747261
http://dx.doi.org/10.1097/GOX.0000000000004360
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