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Successful Treatment of Wound Dehiscence by Innovative Type 1 Collagen Flowable Gel: A Case Report
The growing demand for postbariatric body-contouring surgery after massive weight loss goes hand-in-hand with an increase in wound complications. Consequently, surgical reoperation or conservative management is necessary and represents a difficult challenge to healthcare professionals. Moreover, it...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9208871/ https://www.ncbi.nlm.nih.gov/pubmed/35747261 http://dx.doi.org/10.1097/GOX.0000000000004360 |
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author | Ferraro, Giuseppe A. Lanzano, Giuseppe Grella, Elisa Gubitosi, Adelmo Nicoletti, Giovanni F. |
author_facet | Ferraro, Giuseppe A. Lanzano, Giuseppe Grella, Elisa Gubitosi, Adelmo Nicoletti, Giovanni F. |
author_sort | Ferraro, Giuseppe A. |
collection | PubMed |
description | The growing demand for postbariatric body-contouring surgery after massive weight loss goes hand-in-hand with an increase in wound complications. Consequently, surgical reoperation or conservative management is necessary and represents a difficult challenge to healthcare professionals. Moreover, it is well known that postbariatric patients present aberrant wound healing due to multifactorial causes, such as preoperative illness, nutritional deficiencies, and vascular disease. To treat such complex wounds, several methods have been recommended, such as the use of negative pressure wound therapy, tissue-engineered skin substitutes, and collagen-based wound dressings. The case presented here is of a patient with deep wound dehiscence of the inner left thigh, 1 week after a medial thigh lift procedure, successfully managed with Vergenix Flowable Gel, a human recombinant type I collagen produced in plants. After 2 weeks of treatment, wound dehiscence was replaced with granulation tissue, and after 4 weeks, the patient was completely healed, with an acceptable aesthetic outcome of the surgical scar. |
format | Online Article Text |
id | pubmed-9208871 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-92088712022-06-22 Successful Treatment of Wound Dehiscence by Innovative Type 1 Collagen Flowable Gel: A Case Report Ferraro, Giuseppe A. Lanzano, Giuseppe Grella, Elisa Gubitosi, Adelmo Nicoletti, Giovanni F. Plast Reconstr Surg Glob Open Reconstructive The growing demand for postbariatric body-contouring surgery after massive weight loss goes hand-in-hand with an increase in wound complications. Consequently, surgical reoperation or conservative management is necessary and represents a difficult challenge to healthcare professionals. Moreover, it is well known that postbariatric patients present aberrant wound healing due to multifactorial causes, such as preoperative illness, nutritional deficiencies, and vascular disease. To treat such complex wounds, several methods have been recommended, such as the use of negative pressure wound therapy, tissue-engineered skin substitutes, and collagen-based wound dressings. The case presented here is of a patient with deep wound dehiscence of the inner left thigh, 1 week after a medial thigh lift procedure, successfully managed with Vergenix Flowable Gel, a human recombinant type I collagen produced in plants. After 2 weeks of treatment, wound dehiscence was replaced with granulation tissue, and after 4 weeks, the patient was completely healed, with an acceptable aesthetic outcome of the surgical scar. Lippincott Williams & Wilkins 2022-06-20 /pmc/articles/PMC9208871/ /pubmed/35747261 http://dx.doi.org/10.1097/GOX.0000000000004360 Text en Copyright © 2022 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of The American Society of Plastic Surgeons. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. |
spellingShingle | Reconstructive Ferraro, Giuseppe A. Lanzano, Giuseppe Grella, Elisa Gubitosi, Adelmo Nicoletti, Giovanni F. Successful Treatment of Wound Dehiscence by Innovative Type 1 Collagen Flowable Gel: A Case Report |
title | Successful Treatment of Wound Dehiscence by Innovative Type 1 Collagen Flowable Gel: A Case Report |
title_full | Successful Treatment of Wound Dehiscence by Innovative Type 1 Collagen Flowable Gel: A Case Report |
title_fullStr | Successful Treatment of Wound Dehiscence by Innovative Type 1 Collagen Flowable Gel: A Case Report |
title_full_unstemmed | Successful Treatment of Wound Dehiscence by Innovative Type 1 Collagen Flowable Gel: A Case Report |
title_short | Successful Treatment of Wound Dehiscence by Innovative Type 1 Collagen Flowable Gel: A Case Report |
title_sort | successful treatment of wound dehiscence by innovative type 1 collagen flowable gel: a case report |
topic | Reconstructive |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9208871/ https://www.ncbi.nlm.nih.gov/pubmed/35747261 http://dx.doi.org/10.1097/GOX.0000000000004360 |
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