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Ectopic Fetal Liver Tissue in the Placenta of a Twin Pregnancy: A Case Report and Review of Literature

Ectopic liver tissue represents a rare entity and is mostly attributed to events occurring during embryogenesis. Previous case reports documented the presence of fetal liver parenchyma within temporarily developed organs during pregnancy, such as the placenta or the umbilical cord. Moreover, the ter...

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Autores principales: Leucă, Andrei, Demetter, Pieter, Boulay, Amélie, Vanden Houte, Katherina, Segers, Valérie, Verset, Laurine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9208982/
https://www.ncbi.nlm.nih.gov/pubmed/35733647
http://dx.doi.org/10.1155/2022/1966025
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author Leucă, Andrei
Demetter, Pieter
Boulay, Amélie
Vanden Houte, Katherina
Segers, Valérie
Verset, Laurine
author_facet Leucă, Andrei
Demetter, Pieter
Boulay, Amélie
Vanden Houte, Katherina
Segers, Valérie
Verset, Laurine
author_sort Leucă, Andrei
collection PubMed
description Ectopic liver tissue represents a rare entity and is mostly attributed to events occurring during embryogenesis. Previous case reports documented the presence of fetal liver parenchyma within temporarily developed organs during pregnancy, such as the placenta or the umbilical cord. Moreover, the terminology of these benign findings varies from “ectopic liver” to “hepatocellular adenoma-like neoplasm” or “hepatocellular adenoma”. Ancillary tests performed on these lesions have shown positive immunohistochemical staining for hepatocellular origin marker HepPar-1. Only one recent case report comprising molecular analysis showed no beta-catenin gain-of-function mutation. We report a case of ectopic liver in one placenta of a twin pregnancy, with an updated review of literature.
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spelling pubmed-92089822022-06-21 Ectopic Fetal Liver Tissue in the Placenta of a Twin Pregnancy: A Case Report and Review of Literature Leucă, Andrei Demetter, Pieter Boulay, Amélie Vanden Houte, Katherina Segers, Valérie Verset, Laurine Case Rep Pathol Case Report Ectopic liver tissue represents a rare entity and is mostly attributed to events occurring during embryogenesis. Previous case reports documented the presence of fetal liver parenchyma within temporarily developed organs during pregnancy, such as the placenta or the umbilical cord. Moreover, the terminology of these benign findings varies from “ectopic liver” to “hepatocellular adenoma-like neoplasm” or “hepatocellular adenoma”. Ancillary tests performed on these lesions have shown positive immunohistochemical staining for hepatocellular origin marker HepPar-1. Only one recent case report comprising molecular analysis showed no beta-catenin gain-of-function mutation. We report a case of ectopic liver in one placenta of a twin pregnancy, with an updated review of literature. Hindawi 2022-06-13 /pmc/articles/PMC9208982/ /pubmed/35733647 http://dx.doi.org/10.1155/2022/1966025 Text en Copyright © 2022 Andrei Leucă et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Leucă, Andrei
Demetter, Pieter
Boulay, Amélie
Vanden Houte, Katherina
Segers, Valérie
Verset, Laurine
Ectopic Fetal Liver Tissue in the Placenta of a Twin Pregnancy: A Case Report and Review of Literature
title Ectopic Fetal Liver Tissue in the Placenta of a Twin Pregnancy: A Case Report and Review of Literature
title_full Ectopic Fetal Liver Tissue in the Placenta of a Twin Pregnancy: A Case Report and Review of Literature
title_fullStr Ectopic Fetal Liver Tissue in the Placenta of a Twin Pregnancy: A Case Report and Review of Literature
title_full_unstemmed Ectopic Fetal Liver Tissue in the Placenta of a Twin Pregnancy: A Case Report and Review of Literature
title_short Ectopic Fetal Liver Tissue in the Placenta of a Twin Pregnancy: A Case Report and Review of Literature
title_sort ectopic fetal liver tissue in the placenta of a twin pregnancy: a case report and review of literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9208982/
https://www.ncbi.nlm.nih.gov/pubmed/35733647
http://dx.doi.org/10.1155/2022/1966025
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