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Allergic Bronchopulmonary Aspergillosis with an Atypical Mass-Like Presentation

Allergic bronchopulmonary aspergillosis is an uncommon condition characterized by airway hypersensitivity to Aspergillus fumigatus, resulting in worsening asthma control and bronchiectasis progression. It is associated with various radiological features. Here, we describe a 53-year-old lady with aty...

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Autores principales: Mahmoud, Mahmoud Ibrahim, Elfaki, Alaeldin, Alhaj, Ziad A., Said, Abir Hamad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9208993/
https://www.ncbi.nlm.nih.gov/pubmed/35733508
http://dx.doi.org/10.1155/2022/3627202
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author Mahmoud, Mahmoud Ibrahim
Elfaki, Alaeldin
Alhaj, Ziad A.
Said, Abir Hamad
author_facet Mahmoud, Mahmoud Ibrahim
Elfaki, Alaeldin
Alhaj, Ziad A.
Said, Abir Hamad
author_sort Mahmoud, Mahmoud Ibrahim
collection PubMed
description Allergic bronchopulmonary aspergillosis is an uncommon condition characterized by airway hypersensitivity to Aspergillus fumigatus, resulting in worsening asthma control and bronchiectasis progression. It is associated with various radiological features. Here, we describe a 53-year-old lady with atypical CT chest finding as soft tissue density masses in both lungs evaluated initially as a lung tumour. The diagnosis was particularly challenging given the history of undiagnosed asthma. Nevertheless, bronchoscopy findings of mucus impaction and blood eosinophilia redirect the clinical thinking toward ABPA. Laboratory examination showed elevated total IgE, Aspergillus fumigatus IgE, and Aspergillus niger IgE. Shortly after treatments with systemic steroids, our patient showed a symptomatic improvement. Moreover, subsequent follow-up showed a resolution of the radiological opacities.
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spelling pubmed-92089932022-06-21 Allergic Bronchopulmonary Aspergillosis with an Atypical Mass-Like Presentation Mahmoud, Mahmoud Ibrahim Elfaki, Alaeldin Alhaj, Ziad A. Said, Abir Hamad Case Rep Pulmonol Case Report Allergic bronchopulmonary aspergillosis is an uncommon condition characterized by airway hypersensitivity to Aspergillus fumigatus, resulting in worsening asthma control and bronchiectasis progression. It is associated with various radiological features. Here, we describe a 53-year-old lady with atypical CT chest finding as soft tissue density masses in both lungs evaluated initially as a lung tumour. The diagnosis was particularly challenging given the history of undiagnosed asthma. Nevertheless, bronchoscopy findings of mucus impaction and blood eosinophilia redirect the clinical thinking toward ABPA. Laboratory examination showed elevated total IgE, Aspergillus fumigatus IgE, and Aspergillus niger IgE. Shortly after treatments with systemic steroids, our patient showed a symptomatic improvement. Moreover, subsequent follow-up showed a resolution of the radiological opacities. Hindawi 2022-06-13 /pmc/articles/PMC9208993/ /pubmed/35733508 http://dx.doi.org/10.1155/2022/3627202 Text en Copyright © 2022 Mahmoud Ibrahim Mahmoud et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Mahmoud, Mahmoud Ibrahim
Elfaki, Alaeldin
Alhaj, Ziad A.
Said, Abir Hamad
Allergic Bronchopulmonary Aspergillosis with an Atypical Mass-Like Presentation
title Allergic Bronchopulmonary Aspergillosis with an Atypical Mass-Like Presentation
title_full Allergic Bronchopulmonary Aspergillosis with an Atypical Mass-Like Presentation
title_fullStr Allergic Bronchopulmonary Aspergillosis with an Atypical Mass-Like Presentation
title_full_unstemmed Allergic Bronchopulmonary Aspergillosis with an Atypical Mass-Like Presentation
title_short Allergic Bronchopulmonary Aspergillosis with an Atypical Mass-Like Presentation
title_sort allergic bronchopulmonary aspergillosis with an atypical mass-like presentation
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9208993/
https://www.ncbi.nlm.nih.gov/pubmed/35733508
http://dx.doi.org/10.1155/2022/3627202
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