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205 Targeting Homologous Repair to Overcome Genotoxic Therapy Resistance in Pancreatic Cancer

OBJECTIVES/GOALS: Pancreatic ductal adenocarcinoma (PDAC) is a relatively radioresistant disease, and inhibition of DNA homologous recombination (HR) repair in combination with radiation therapy (RT) is a potentially attractive strategy to overcome radioresistance. We have found that the expression...

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Detalles Bibliográficos
Autores principales: Wolfe, Adam, Zuniga, Oscar, West, Kirk, Leung, Justin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209035/
http://dx.doi.org/10.1017/cts.2022.107