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205 Targeting Homologous Repair to Overcome Genotoxic Therapy Resistance in Pancreatic Cancer
OBJECTIVES/GOALS: Pancreatic ductal adenocarcinoma (PDAC) is a relatively radioresistant disease, and inhibition of DNA homologous recombination (HR) repair in combination with radiation therapy (RT) is a potentially attractive strategy to overcome radioresistance. We have found that the expression...
Autores principales: | Wolfe, Adam, Zuniga, Oscar, West, Kirk, Leung, Justin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cambridge University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209035/ http://dx.doi.org/10.1017/cts.2022.107 |
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