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343 Brain-derived Extracellular Vesicles: A Novel Biomarker of CNS Metals Load with Applications in Identifying Neurodegenerative Diseases

OBJECTIVES/GOALS: This study aims to develop a method to examine whether blood-borne CNS-EV metal cargoes can serve as reliable biomarkers of CNS metal load and reveal a link between metal load and ALS development (i.e., neurodegenerative disease development). METHODS/STUDY POPULATION: CNS-EVs were...

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Detalles Bibliográficos
Autores principales: Saxena, Roheeni, Saglimbeni, Brianna, Strait, Madeleine, Alayyoub, Mohammad, Comfort, Nicole, Re, Diane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209220/
http://dx.doi.org/10.1017/cts.2022.195