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457 Semaphorin7a expression in breast cancer promotes susceptibility to immune checkpoint blockade

OBJECTIVES/GOALS: The goal of this study is to decipher the mechanisms by which breast cancers evade the immune system to facilitate metastasis through the lymphatic vasculature. We believe this is caused, in part, by semaphorin 7A (SEMA7A) as its expression is associated with increased lymphatic ve...

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Detalles Bibliográficos
Autores principales: Elder, Alan, Stoller, Alexander, Kines, Kelsey, Lyons, Traci
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209226/
http://dx.doi.org/10.1017/cts.2022.267