Reovirus mutant jin-3 exhibits lytic and immune-stimulatory effects in preclinical human prostate cancer models

Treatment of castration-resistant prostate cancer remains a challenging clinical problem. Despite the promising effects of immunotherapy in other solid cancers, prostate cancer has remained largely unresponsive. Oncolytic viruses represent a promising therapeutic avenue, as oncolytic virus treatment...

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Detalles Bibliográficos
Autores principales: van de Merbel, Arjanneke F., van der Horst, Geertje, van der Mark, Maaike H., Bots, Selas T. F., van den Wollenberg, Diana J. M., de Ridder, Corrina M. A., Stuurman, Debra, Aalders, Tilly, Erkens-Schulz, Sigrun, van Montfoort, Nadine, Karthaus, Wouter R., Mehra, Niven, Smits, Minke, Schalken, Jack A., van Weerden, Wytske M., Hoeben, Rob C., van der Pluijm, Gabri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209329/
https://www.ncbi.nlm.nih.gov/pubmed/34135475
http://dx.doi.org/10.1038/s41417-021-00360-2

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