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Decision-making psychological state and characteristic of proxies of thrombolytic patients: a pilot study

Intravenous thrombolysis is the preferred treatment modality for acute ischemic stroke. In China, written informed consent from patients or proxies must be obtained before intravenous thrombolysis is performed, which always leads to in-hospital delay of thrombolysis. To explore the relationship betw...

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Autores principales: Yuanli, Guo, Yanjin, Liu, Lina, Guo, Xiaofang, Dong, Caixia, Yang, Min, Wang, Huanhuan, Gao, Peihua, Lv, Keke, Ma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209408/
https://www.ncbi.nlm.nih.gov/pubmed/35725751
http://dx.doi.org/10.1038/s41598-022-14124-x
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author Yuanli, Guo
Yanjin, Liu
Lina, Guo
Xiaofang, Dong
Caixia, Yang
Min, Wang
Huanhuan, Gao
Peihua, Lv
Keke, Ma
author_facet Yuanli, Guo
Yanjin, Liu
Lina, Guo
Xiaofang, Dong
Caixia, Yang
Min, Wang
Huanhuan, Gao
Peihua, Lv
Keke, Ma
author_sort Yuanli, Guo
collection PubMed
description Intravenous thrombolysis is the preferred treatment modality for acute ischemic stroke. In China, written informed consent from patients or proxies must be obtained before intravenous thrombolysis is performed, which always leads to in-hospital delay of thrombolysis. To explore the relationship between characteristics of thrombolysis decision-making and psychological states of proxies of AIS patients. This was a pilot study. 231 proxies of AIS patients were recruited, including 147 males and 84 females. STAI, WFPTS, CAOT, CPS, C-DCS and time-consuming of decision-making were collected by trained nurses during the period from signing informed consent to thrombolysis finished. The general information was collected within 24 h after admission. Pearson correlation analysis and the Ridge regression analysis were used to explore the correlation and causality between psychological indicators (STAI, WFPTS, CAOT, CPS) and decision-making characteristics (C-DCS, Time consuming). Structural equation modeling was used to explore the direct and indirect effect of psychological factors on decision-making characteristics. The mean of anxiety, trust in physicians, and decision conflict were 49.20 ± 9.50, 37.83 ± 6.63 and 30.60 ± 14.77, respectively. The CAOT was associated with C-DCS through the mediation of STAI and WFPTS (p < 0.001). The CAOT was associated with time-consuming through the mediation of STAI, WFPTS and CPS (p < 0.05). The CAOT, STAI and WFPTS were associated with C-DCS (p < 0.05), and STAI, WFPTS and CPS were associated with time-consuming (p < 0.01). The proxy of patients with acute ischemic stroke had severe decision conflict in thrombolysis decision-making. The psychological state was associated with decision conflict and the time-consuming. Medical staff should explore methods to release the anxiety and increase the trust in physicians to reduce the decision-making conflict and time-consuming, which could promote the smooth progress of the informed consent.
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spelling pubmed-92094082022-06-22 Decision-making psychological state and characteristic of proxies of thrombolytic patients: a pilot study Yuanli, Guo Yanjin, Liu Lina, Guo Xiaofang, Dong Caixia, Yang Min, Wang Huanhuan, Gao Peihua, Lv Keke, Ma Sci Rep Article Intravenous thrombolysis is the preferred treatment modality for acute ischemic stroke. In China, written informed consent from patients or proxies must be obtained before intravenous thrombolysis is performed, which always leads to in-hospital delay of thrombolysis. To explore the relationship between characteristics of thrombolysis decision-making and psychological states of proxies of AIS patients. This was a pilot study. 231 proxies of AIS patients were recruited, including 147 males and 84 females. STAI, WFPTS, CAOT, CPS, C-DCS and time-consuming of decision-making were collected by trained nurses during the period from signing informed consent to thrombolysis finished. The general information was collected within 24 h after admission. Pearson correlation analysis and the Ridge regression analysis were used to explore the correlation and causality between psychological indicators (STAI, WFPTS, CAOT, CPS) and decision-making characteristics (C-DCS, Time consuming). Structural equation modeling was used to explore the direct and indirect effect of psychological factors on decision-making characteristics. The mean of anxiety, trust in physicians, and decision conflict were 49.20 ± 9.50, 37.83 ± 6.63 and 30.60 ± 14.77, respectively. The CAOT was associated with C-DCS through the mediation of STAI and WFPTS (p < 0.001). The CAOT was associated with time-consuming through the mediation of STAI, WFPTS and CPS (p < 0.05). The CAOT, STAI and WFPTS were associated with C-DCS (p < 0.05), and STAI, WFPTS and CPS were associated with time-consuming (p < 0.01). The proxy of patients with acute ischemic stroke had severe decision conflict in thrombolysis decision-making. The psychological state was associated with decision conflict and the time-consuming. Medical staff should explore methods to release the anxiety and increase the trust in physicians to reduce the decision-making conflict and time-consuming, which could promote the smooth progress of the informed consent. Nature Publishing Group UK 2022-06-20 /pmc/articles/PMC9209408/ /pubmed/35725751 http://dx.doi.org/10.1038/s41598-022-14124-x Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Yuanli, Guo
Yanjin, Liu
Lina, Guo
Xiaofang, Dong
Caixia, Yang
Min, Wang
Huanhuan, Gao
Peihua, Lv
Keke, Ma
Decision-making psychological state and characteristic of proxies of thrombolytic patients: a pilot study
title Decision-making psychological state and characteristic of proxies of thrombolytic patients: a pilot study
title_full Decision-making psychological state and characteristic of proxies of thrombolytic patients: a pilot study
title_fullStr Decision-making psychological state and characteristic of proxies of thrombolytic patients: a pilot study
title_full_unstemmed Decision-making psychological state and characteristic of proxies of thrombolytic patients: a pilot study
title_short Decision-making psychological state and characteristic of proxies of thrombolytic patients: a pilot study
title_sort decision-making psychological state and characteristic of proxies of thrombolytic patients: a pilot study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209408/
https://www.ncbi.nlm.nih.gov/pubmed/35725751
http://dx.doi.org/10.1038/s41598-022-14124-x
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