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Artificial intelligence guided conformational mining of intrinsically disordered proteins
Artificial intelligence recently achieved the breakthrough of predicting the three-dimensional structures of proteins. The next frontier is presented by intrinsically disordered proteins (IDPs), which, representing 30% to 50% of proteomes, readily access vast conformational space. Molecular dynamics...
Autores principales: | Gupta, Aayush, Dey, Souvik, Hicks, Alan, Zhou, Huan-Xiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209487/ https://www.ncbi.nlm.nih.gov/pubmed/35725761 http://dx.doi.org/10.1038/s42003-022-03562-y |
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