EphB4 and ephrinB2 act in opposition in the head and neck tumor microenvironment

Differential outcomes of EphB4-ephrinB2 signaling offers formidable challenge for the development of cancer therapeutics. Here, we interrogate the effects of targeting EphB4 and ephrinB2 in head and neck squamous cell carcinoma (HNSCC) and within its microenvironment using genetically engineered mic...

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Detalles Bibliográficos
Autores principales: Bhatia, Shilpa, Nguyen, Diemmy, Darragh, Laurel B., Van Court, Benjamin, Sharma, Jaspreet, Knitz, Michael W., Piper, Miles, Bukkapatnam, Sanjana, Gadwa, Jacob, Bickett, Thomas E., Bhuvane, Shiv, Corbo, Sophia, Wu, Brian, Lee, Yichien, Fujita, Mayumi, Joshi, Molishree, Heasley, Lynn E., Ferris, Robert L., Rodriguez, Olga, Albanese, Christopher, Kapoor, Mohit, Pasquale, Elena B., Karam, Sana D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209511/
https://www.ncbi.nlm.nih.gov/pubmed/35725568
http://dx.doi.org/10.1038/s41467-022-31124-7

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