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Murine double minute 2 aggravates adipose tissue dysfunction through ubiquitin-mediated six-transmembrane epithelial antigen of prostate 4 degradation

Healthy adipose tissue is crucial to maintain normal energy homeostasis. Little is known about the role of murine double minute 2 (MDM2), an E3 ubiquitin ligase and has been highlighted in oncopathology, in adipose tissue. Our results indicated that MDM2 expression was associated with nutritional st...

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Detalles Bibliográficos
Autores principales: Zhao, Wei, Xu, Qiang, Yang, Jiahui, Xie, Xianghong, Li, Chunmei, Zhang, Weihong, Chen, Enhui, Guo, Yanfang, Gao, Mingyue, Shi, Jie, Zhang, Huabing, Yao, Hong, Li, Meixia, Yan, Li, Fang, Fude, Wu, Wenming, Liu, Xiaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209722/
https://www.ncbi.nlm.nih.gov/pubmed/35747386
http://dx.doi.org/10.1016/j.isci.2022.104544