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Leptomeningeal disease and tumor dissemination in a murine diffuse intrinsic pontine glioma model: implications for the study of the tumor-cerebrospinal fluid-ependymal microenvironment

BACKGROUND: Leptomeningeal disease and hydrocephalus are present in up to 30% of patients with diffuse intrinsic pontine glioma (DIPG), however there are no animal models of cerebrospinal fluid (CSF) dissemination. As the tumor–CSF–ependymal microenvironment may play an important role in tumor patho...

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Detalles Bibliográficos
Autores principales:	Pan, Shelei, Ye, Dezhuang, Yue, Yimei, Yang, Lihua, Pacia, Christopher P, DeFreitas, Dakota, Esakky, Prabagaran, Dahiya, Sonika, Limbrick, David D, Rubin, Joshua B, Chen, Hong, Strahle, Jennifer M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Basic and Translational Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209751/ https://www.ncbi.nlm.nih.gov/pubmed/35733516 http://dx.doi.org/10.1093/noajnl/vdac059

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