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New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources
Saccharomyces cerevisiae is used to provide fundamental understanding of eukaryotic genetics, gene product function, and cellular biological processes. Saccharomyces Genome Database (SGD) has been supporting the yeast research community since 1993, serving as its de facto hub. Over the years, SGD ha...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209811/ https://www.ncbi.nlm.nih.gov/pubmed/34897464 http://dx.doi.org/10.1093/genetics/iyab224 |
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author | Engel, Stacia R Wong, Edith D Nash, Robert S Aleksander, Suzi Alexander, Micheal Douglass, Eric Karra, Kalpana Miyasato, Stuart R Simison, Matt Skrzypek, Marek S Weng, Shuai Cherry, J Michael |
author_facet | Engel, Stacia R Wong, Edith D Nash, Robert S Aleksander, Suzi Alexander, Micheal Douglass, Eric Karra, Kalpana Miyasato, Stuart R Simison, Matt Skrzypek, Marek S Weng, Shuai Cherry, J Michael |
author_sort | Engel, Stacia R |
collection | PubMed |
description | Saccharomyces cerevisiae is used to provide fundamental understanding of eukaryotic genetics, gene product function, and cellular biological processes. Saccharomyces Genome Database (SGD) has been supporting the yeast research community since 1993, serving as its de facto hub. Over the years, SGD has maintained the genetic nomenclature, chromosome maps, and functional annotation, and developed various tools and methods for analysis and curation of a variety of emerging data types. More recently, SGD and six other model organism focused knowledgebases have come together to create the Alliance of Genome Resources to develop sustainable genome information resources that promote and support the use of various model organisms to understand the genetic and genomic bases of human biology and disease. Here we describe recent activities at SGD, including the latest reference genome annotation update, the development of a curation system for mutant alleles, and new pages addressing homology across model organisms as well as the use of yeast to study human disease. |
format | Online Article Text |
id | pubmed-9209811 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-92098112022-06-21 New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources Engel, Stacia R Wong, Edith D Nash, Robert S Aleksander, Suzi Alexander, Micheal Douglass, Eric Karra, Kalpana Miyasato, Stuart R Simison, Matt Skrzypek, Marek S Weng, Shuai Cherry, J Michael Genetics Knowledgebase and Database Resources Saccharomyces cerevisiae is used to provide fundamental understanding of eukaryotic genetics, gene product function, and cellular biological processes. Saccharomyces Genome Database (SGD) has been supporting the yeast research community since 1993, serving as its de facto hub. Over the years, SGD has maintained the genetic nomenclature, chromosome maps, and functional annotation, and developed various tools and methods for analysis and curation of a variety of emerging data types. More recently, SGD and six other model organism focused knowledgebases have come together to create the Alliance of Genome Resources to develop sustainable genome information resources that promote and support the use of various model organisms to understand the genetic and genomic bases of human biology and disease. Here we describe recent activities at SGD, including the latest reference genome annotation update, the development of a curation system for mutant alleles, and new pages addressing homology across model organisms as well as the use of yeast to study human disease. Oxford University Press 2021-12-13 /pmc/articles/PMC9209811/ /pubmed/34897464 http://dx.doi.org/10.1093/genetics/iyab224 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of Genetics Society of America. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Knowledgebase and Database Resources Engel, Stacia R Wong, Edith D Nash, Robert S Aleksander, Suzi Alexander, Micheal Douglass, Eric Karra, Kalpana Miyasato, Stuart R Simison, Matt Skrzypek, Marek S Weng, Shuai Cherry, J Michael New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources |
title | New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources |
title_full | New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources |
title_fullStr | New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources |
title_full_unstemmed | New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources |
title_short | New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources |
title_sort | new data and collaborations at the saccharomyces genome database: updated reference genome, alleles, and the alliance of genome resources |
topic | Knowledgebase and Database Resources |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209811/ https://www.ncbi.nlm.nih.gov/pubmed/34897464 http://dx.doi.org/10.1093/genetics/iyab224 |
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