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New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Saccharomyces cerevisiae is used to provide fundamental understanding of eukaryotic genetics, gene product function, and cellular biological processes. Saccharomyces Genome Database (SGD) has been supporting the yeast research community since 1993, serving as its de facto hub. Over the years, SGD ha...

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Autores principales: Engel, Stacia R, Wong, Edith D, Nash, Robert S, Aleksander, Suzi, Alexander, Micheal, Douglass, Eric, Karra, Kalpana, Miyasato, Stuart R, Simison, Matt, Skrzypek, Marek S, Weng, Shuai, Cherry, J Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209811/
https://www.ncbi.nlm.nih.gov/pubmed/34897464
http://dx.doi.org/10.1093/genetics/iyab224
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author Engel, Stacia R
Wong, Edith D
Nash, Robert S
Aleksander, Suzi
Alexander, Micheal
Douglass, Eric
Karra, Kalpana
Miyasato, Stuart R
Simison, Matt
Skrzypek, Marek S
Weng, Shuai
Cherry, J Michael
author_facet Engel, Stacia R
Wong, Edith D
Nash, Robert S
Aleksander, Suzi
Alexander, Micheal
Douglass, Eric
Karra, Kalpana
Miyasato, Stuart R
Simison, Matt
Skrzypek, Marek S
Weng, Shuai
Cherry, J Michael
author_sort Engel, Stacia R
collection PubMed
description Saccharomyces cerevisiae is used to provide fundamental understanding of eukaryotic genetics, gene product function, and cellular biological processes. Saccharomyces Genome Database (SGD) has been supporting the yeast research community since 1993, serving as its de facto hub. Over the years, SGD has maintained the genetic nomenclature, chromosome maps, and functional annotation, and developed various tools and methods for analysis and curation of a variety of emerging data types. More recently, SGD and six other model organism focused knowledgebases have come together to create the Alliance of Genome Resources to develop sustainable genome information resources that promote and support the use of various model organisms to understand the genetic and genomic bases of human biology and disease. Here we describe recent activities at SGD, including the latest reference genome annotation update, the development of a curation system for mutant alleles, and new pages addressing homology across model organisms as well as the use of yeast to study human disease.
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spelling pubmed-92098112022-06-21 New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources Engel, Stacia R Wong, Edith D Nash, Robert S Aleksander, Suzi Alexander, Micheal Douglass, Eric Karra, Kalpana Miyasato, Stuart R Simison, Matt Skrzypek, Marek S Weng, Shuai Cherry, J Michael Genetics Knowledgebase and Database Resources Saccharomyces cerevisiae is used to provide fundamental understanding of eukaryotic genetics, gene product function, and cellular biological processes. Saccharomyces Genome Database (SGD) has been supporting the yeast research community since 1993, serving as its de facto hub. Over the years, SGD has maintained the genetic nomenclature, chromosome maps, and functional annotation, and developed various tools and methods for analysis and curation of a variety of emerging data types. More recently, SGD and six other model organism focused knowledgebases have come together to create the Alliance of Genome Resources to develop sustainable genome information resources that promote and support the use of various model organisms to understand the genetic and genomic bases of human biology and disease. Here we describe recent activities at SGD, including the latest reference genome annotation update, the development of a curation system for mutant alleles, and new pages addressing homology across model organisms as well as the use of yeast to study human disease. Oxford University Press 2021-12-13 /pmc/articles/PMC9209811/ /pubmed/34897464 http://dx.doi.org/10.1093/genetics/iyab224 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of Genetics Society of America. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Knowledgebase and Database Resources
Engel, Stacia R
Wong, Edith D
Nash, Robert S
Aleksander, Suzi
Alexander, Micheal
Douglass, Eric
Karra, Kalpana
Miyasato, Stuart R
Simison, Matt
Skrzypek, Marek S
Weng, Shuai
Cherry, J Michael
New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources
title New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources
title_full New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources
title_fullStr New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources
title_full_unstemmed New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources
title_short New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources
title_sort new data and collaborations at the saccharomyces genome database: updated reference genome, alleles, and the alliance of genome resources
topic Knowledgebase and Database Resources
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209811/
https://www.ncbi.nlm.nih.gov/pubmed/34897464
http://dx.doi.org/10.1093/genetics/iyab224
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