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IgG4-Related Lung Disease Exhibiting the Invasion into the Diaphragm: A Case Report
Immunoglobulin G4-related disease (IgG4-RD) is a fibroinflammatory condition which involves various organs. This is a very rare case of IgG4-related lung disease (IgG4-RLD) with the invasion into diaphragm. The patient was a 71-year-old man with a long-term exposure to asbestos who had a mass shadow...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Editorial Committee of Annals of Thoracic and Cardiovascular Surgery
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209885/ https://www.ncbi.nlm.nih.gov/pubmed/32101810 http://dx.doi.org/10.5761/atcs.cr.19-00244 |
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author | Ono, Yuki Toyokawa, Gouji Tagawa, Tetsuzo Ijichi, Kayo Oda, Yoshinao Mori, Masaki |
author_facet | Ono, Yuki Toyokawa, Gouji Tagawa, Tetsuzo Ijichi, Kayo Oda, Yoshinao Mori, Masaki |
author_sort | Ono, Yuki |
collection | PubMed |
description | Immunoglobulin G4-related disease (IgG4-RD) is a fibroinflammatory condition which involves various organs. This is a very rare case of IgG4-related lung disease (IgG4-RLD) with the invasion into diaphragm. The patient was a 71-year-old man with a long-term exposure to asbestos who had a mass shadow in the left lower lung lobe, which was suspected to invade the left diaphragm on computed tomography (CT). Positron emission tomography (PET)/CT also presented an avid intake of fluorodeoxyglucose in the mass, which suspected lung cancer. Although bronchoscopic biopsy could not lead to the definite diagnosis, we performed left lower lobectomy combined with the resection of left diaphragm. The specimen showed the features of IgG4-RLD on pathology: the vein stenosis and fibrosis around the vein, the infiltration of IgG4-positive cells, and IgG cells to IgG4 cells ratio of 40%. Furthermore, there were inflammatory cells infiltrating to the diaphragm. |
format | Online Article Text |
id | pubmed-9209885 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | The Editorial Committee of Annals of Thoracic and Cardiovascular Surgery |
record_format | MEDLINE/PubMed |
spelling | pubmed-92098852022-07-06 IgG4-Related Lung Disease Exhibiting the Invasion into the Diaphragm: A Case Report Ono, Yuki Toyokawa, Gouji Tagawa, Tetsuzo Ijichi, Kayo Oda, Yoshinao Mori, Masaki Ann Thorac Cardiovasc Surg Case Report Immunoglobulin G4-related disease (IgG4-RD) is a fibroinflammatory condition which involves various organs. This is a very rare case of IgG4-related lung disease (IgG4-RLD) with the invasion into diaphragm. The patient was a 71-year-old man with a long-term exposure to asbestos who had a mass shadow in the left lower lung lobe, which was suspected to invade the left diaphragm on computed tomography (CT). Positron emission tomography (PET)/CT also presented an avid intake of fluorodeoxyglucose in the mass, which suspected lung cancer. Although bronchoscopic biopsy could not lead to the definite diagnosis, we performed left lower lobectomy combined with the resection of left diaphragm. The specimen showed the features of IgG4-RLD on pathology: the vein stenosis and fibrosis around the vein, the infiltration of IgG4-positive cells, and IgG cells to IgG4 cells ratio of 40%. Furthermore, there were inflammatory cells infiltrating to the diaphragm. The Editorial Committee of Annals of Thoracic and Cardiovascular Surgery 2020-02-27 2022 /pmc/articles/PMC9209885/ /pubmed/32101810 http://dx.doi.org/10.5761/atcs.cr.19-00244 Text en ©2022 Annals of Thoracic and Cardiovascular Surgery https://creativecommons.org/licenses/by-nc-nd/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial-NonDerivatives International License (https://creativecommons.org/licenses/by-nc-nd/4.0/) |
spellingShingle | Case Report Ono, Yuki Toyokawa, Gouji Tagawa, Tetsuzo Ijichi, Kayo Oda, Yoshinao Mori, Masaki IgG4-Related Lung Disease Exhibiting the Invasion into the Diaphragm: A Case Report |
title | IgG4-Related Lung Disease Exhibiting the Invasion into the Diaphragm: A Case Report |
title_full | IgG4-Related Lung Disease Exhibiting the Invasion into the Diaphragm: A Case Report |
title_fullStr | IgG4-Related Lung Disease Exhibiting the Invasion into the Diaphragm: A Case Report |
title_full_unstemmed | IgG4-Related Lung Disease Exhibiting the Invasion into the Diaphragm: A Case Report |
title_short | IgG4-Related Lung Disease Exhibiting the Invasion into the Diaphragm: A Case Report |
title_sort | igg4-related lung disease exhibiting the invasion into the diaphragm: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209885/ https://www.ncbi.nlm.nih.gov/pubmed/32101810 http://dx.doi.org/10.5761/atcs.cr.19-00244 |
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