A Case of Papuloerythroderma Successfully Treated with Dupilumab

Papuloerythroderma is an erythroderma characterized by the composition of dense paving stone shape papules and intertriginous uninvolved skin on the abdominal wall and is often intractable and accompanied by itching. Topical or oral corticosteroids are treatment measures, but immunosuppressive drugs...

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Detalles Bibliográficos
Autores principales: Mizuno, Ayaka, Habe, Koji, Matsushima, Yoshiaki, Kondo, Makoto, Yamanaka, Keiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2022
Materias:
Single Case
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209986/
https://www.ncbi.nlm.nih.gov/pubmed/35813837
http://dx.doi.org/10.1159/000524716
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author Mizuno, Ayaka
Habe, Koji
Matsushima, Yoshiaki
Kondo, Makoto
Yamanaka, Keiichi
author_facet Mizuno, Ayaka
Habe, Koji
Matsushima, Yoshiaki
Kondo, Makoto
Yamanaka, Keiichi
author_sort Mizuno, Ayaka
collection PubMed
description Papuloerythroderma is an erythroderma characterized by the composition of dense paving stone shape papules and intertriginous uninvolved skin on the abdominal wall and is often intractable and accompanied by itching. Topical or oral corticosteroids are treatment measures, but immunosuppressive drugs are sometimes required. Herein, we report a case of papuloerythroderma treated with dupilumab, a completely humanized immunoglobulin monoclonal antibody against interleukin-4 receptor subunit α (IL-4Rα) of IL-4 and IL-13 receptors, with rapid and marked improvement. Dupilumab is one of the treatment options to treat refractory papuloerythroderma.
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spelling pubmed-92099862022-07-08 A Case of Papuloerythroderma Successfully Treated with Dupilumab Mizuno, Ayaka Habe, Koji Matsushima, Yoshiaki Kondo, Makoto Yamanaka, Keiichi Case Rep Dermatol Single Case Papuloerythroderma is an erythroderma characterized by the composition of dense paving stone shape papules and intertriginous uninvolved skin on the abdominal wall and is often intractable and accompanied by itching. Topical or oral corticosteroids are treatment measures, but immunosuppressive drugs are sometimes required. Herein, we report a case of papuloerythroderma treated with dupilumab, a completely humanized immunoglobulin monoclonal antibody against interleukin-4 receptor subunit α (IL-4Rα) of IL-4 and IL-13 receptors, with rapid and marked improvement. Dupilumab is one of the treatment options to treat refractory papuloerythroderma. S. Karger AG 2022-05-23 /pmc/articles/PMC9209986/ /pubmed/35813837 http://dx.doi.org/10.1159/000524716 Text en Copyright © 2022 by S. Karger AG, Basel https://creativecommons.org/licenses/by-nc/4.0/This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Single Case
Mizuno, Ayaka
Habe, Koji
Matsushima, Yoshiaki
Kondo, Makoto
Yamanaka, Keiichi
A Case of Papuloerythroderma Successfully Treated with Dupilumab
title A Case of Papuloerythroderma Successfully Treated with Dupilumab
title_full A Case of Papuloerythroderma Successfully Treated with Dupilumab
title_fullStr A Case of Papuloerythroderma Successfully Treated with Dupilumab
title_full_unstemmed A Case of Papuloerythroderma Successfully Treated with Dupilumab
title_short A Case of Papuloerythroderma Successfully Treated with Dupilumab
title_sort case of papuloerythroderma successfully treated with dupilumab
topic Single Case
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209986/
https://www.ncbi.nlm.nih.gov/pubmed/35813837
http://dx.doi.org/10.1159/000524716
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