Acute Liver Failure after Treatment with Rivaroxaban for Aortic Thrombosis Associated with COVID-19 Infection and Methylenetetrahydrofolate Reductase Gene Polymorphism (C677T)

Coronavirus disease-2019 (COVID-19) has become associated with prothrombotic state that could lead to severe arterial thrombotic complications. In the case of severe COVID-19 infection, hepatic dysfunction has been observed in more than 50% of patients. In this article, we present a case of aortic t...

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Autores principales: Jukic, Ivana, Bozic, Dorotea, Lalovac, Milos, Pavicic Ivelja, Mirela, Radic, Mislav, Sundov, Zeljko, Vukovic, Jonatan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2022
Materias:
Single Case
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209999/
https://www.ncbi.nlm.nih.gov/pubmed/35814800
http://dx.doi.org/10.1159/000524791
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author Jukic, Ivana
Bozic, Dorotea
Lalovac, Milos
Pavicic Ivelja, Mirela
Radic, Mislav
Sundov, Zeljko
Vukovic, Jonatan
author_facet Jukic, Ivana
Bozic, Dorotea
Lalovac, Milos
Pavicic Ivelja, Mirela
Radic, Mislav
Sundov, Zeljko
Vukovic, Jonatan
author_sort Jukic, Ivana
collection PubMed
description Coronavirus disease-2019 (COVID-19) has become associated with prothrombotic state that could lead to severe arterial thrombotic complications. In the case of severe COVID-19 infection, hepatic dysfunction has been observed in more than 50% of patients. In this article, we present a case of aortic thrombosis associated with COVID-19 infection and methylenetetrahydrofolate reductase gene polymorphism (C677T) treated with rivaroxaban resulting in acute liver failure with fatal outcome.
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spelling pubmed-92099992022-07-08 Acute Liver Failure after Treatment with Rivaroxaban for Aortic Thrombosis Associated with COVID-19 Infection and Methylenetetrahydrofolate Reductase Gene Polymorphism (C677T) Jukic, Ivana Bozic, Dorotea Lalovac, Milos Pavicic Ivelja, Mirela Radic, Mislav Sundov, Zeljko Vukovic, Jonatan Case Rep Gastroenterol Single Case Coronavirus disease-2019 (COVID-19) has become associated with prothrombotic state that could lead to severe arterial thrombotic complications. In the case of severe COVID-19 infection, hepatic dysfunction has been observed in more than 50% of patients. In this article, we present a case of aortic thrombosis associated with COVID-19 infection and methylenetetrahydrofolate reductase gene polymorphism (C677T) treated with rivaroxaban resulting in acute liver failure with fatal outcome. S. Karger AG 2022-05-23 /pmc/articles/PMC9209999/ /pubmed/35814800 http://dx.doi.org/10.1159/000524791 Text en Copyright © 2022 by S. Karger AG, Basel https://creativecommons.org/licenses/by-nc/4.0/This article is licensed under the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC). Usage and distribution for commercial purposes requires written permission. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
spellingShingle Single Case
Jukic, Ivana
Bozic, Dorotea
Lalovac, Milos
Pavicic Ivelja, Mirela
Radic, Mislav
Sundov, Zeljko
Vukovic, Jonatan
Acute Liver Failure after Treatment with Rivaroxaban for Aortic Thrombosis Associated with COVID-19 Infection and Methylenetetrahydrofolate Reductase Gene Polymorphism (C677T)
title Acute Liver Failure after Treatment with Rivaroxaban for Aortic Thrombosis Associated with COVID-19 Infection and Methylenetetrahydrofolate Reductase Gene Polymorphism (C677T)
title_full Acute Liver Failure after Treatment with Rivaroxaban for Aortic Thrombosis Associated with COVID-19 Infection and Methylenetetrahydrofolate Reductase Gene Polymorphism (C677T)
title_fullStr Acute Liver Failure after Treatment with Rivaroxaban for Aortic Thrombosis Associated with COVID-19 Infection and Methylenetetrahydrofolate Reductase Gene Polymorphism (C677T)
title_full_unstemmed Acute Liver Failure after Treatment with Rivaroxaban for Aortic Thrombosis Associated with COVID-19 Infection and Methylenetetrahydrofolate Reductase Gene Polymorphism (C677T)
title_short Acute Liver Failure after Treatment with Rivaroxaban for Aortic Thrombosis Associated with COVID-19 Infection and Methylenetetrahydrofolate Reductase Gene Polymorphism (C677T)
title_sort acute liver failure after treatment with rivaroxaban for aortic thrombosis associated with covid-19 infection and methylenetetrahydrofolate reductase gene polymorphism (c677t)
topic Single Case
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209999/
https://www.ncbi.nlm.nih.gov/pubmed/35814800
http://dx.doi.org/10.1159/000524791
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