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The potential of pirtobrutinib in multiple B-cell malignancies

Bruton’s tyrosine kinase (BTK) is a critical downstream signaling element from the B-cell receptor (BCR) that has been effectively inhibited in B-cell cancers by irreversible, covalent inhibitors including ibrutinib and acalabrutinib. All FDA-approved covalent BTK inhibitors rely on binding to the c...

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Detalles Bibliográficos
Autores principales:	Jensen, Jeffrey L., Mato, Anthony R., Pena, Camila, Roeker, Lindsey E., Coombs, Catherine C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9210100/ https://www.ncbi.nlm.nih.gov/pubmed/35747462 http://dx.doi.org/10.1177/20406207221101697

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