Cargando…

Gunshot Wounds to the Lumbosacral Spine: Systematic Review and Meta-Analysis

STUDY DESIGN: Systematic review and meta-analysis. OBJECTIVES: Indications for surgical decompression of gunshot wounds to the lumbosacral spine are controversial and based on limited data. METHODS: A systematic review of literature was conducted to identify studies that directly compare neurologic...

Descripción completa

Detalles Bibliográficos
Autores principales: Platt, Andrew, Dafrawy, Mostafa H. El, Lee, Michael J., Herman, Martin H., Ramos, Edwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9210234/
https://www.ncbi.nlm.nih.gov/pubmed/34275384
http://dx.doi.org/10.1177/21925682211030873
_version_ 1784730121896198144
author Platt, Andrew
Dafrawy, Mostafa H. El
Lee, Michael J.
Herman, Martin H.
Ramos, Edwin
author_facet Platt, Andrew
Dafrawy, Mostafa H. El
Lee, Michael J.
Herman, Martin H.
Ramos, Edwin
author_sort Platt, Andrew
collection PubMed
description STUDY DESIGN: Systematic review and meta-analysis. OBJECTIVES: Indications for surgical decompression of gunshot wounds to the lumbosacral spine are controversial and based on limited data. METHODS: A systematic review of literature was conducted to identify studies that directly compare neurologic outcomes following operative and non-operative management of gunshot wounds to the lumbosacral spine. Studies were evaluated for degree of neurologic improvement, complications, and antibiotic usage. An odds ratio and 95% confidence interval were calculated for dichotomous outcomes which were then pooled by random-effects model meta-analysis. RESULTS: Five studies were included that met inclusion criteria. The total rate of neurologic improvement was 72.3% following surgical intervention and 61.7% following non-operative intervention. A random-effects model meta-analysis was carried out which failed to show a statistically significant difference in the rate of neurologic improvement between surgical and non-operative intervention (OR 1.07; 95% CI 0.45, 2.53; P = 0.88). In civilian only studies, a random-effects model meta-analysis failed to show a statistically significant difference in the rate of neurologic improvement between surgical and non-operative intervention (OR 0.75; 95% CI 0.21, 2.72; P = 0.66). Meta-analysis further failed to show a statistically significant difference in the rate of neurologic improvement between patients with either complete (OR 4.13; 95% CI 0.55, 30.80; P = 0.17) or incomplete (OR 0.38; 95% CI 0.10, 1.52; P = 0.17) neurologic injuries who underwent surgical and non-operative intervention. There were no significant differences in the number of infections and other complications between patients who underwent surgical and non-operative intervention. CONCLUSIONS: There were no statistically significant differences in the rate of neurologic improvement between those who underwent surgical or non-operative intervention. Further research is necessary to determine if surgical intervention for gunshot wounds to the lumbosacral spine, including in the case of retained bullet within the spinal canal, is efficacious.
format Online
Article
Text
id pubmed-9210234
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher SAGE Publications
record_format MEDLINE/PubMed
spelling pubmed-92102342022-06-22 Gunshot Wounds to the Lumbosacral Spine: Systematic Review and Meta-Analysis Platt, Andrew Dafrawy, Mostafa H. El Lee, Michael J. Herman, Martin H. Ramos, Edwin Global Spine J Review Articles STUDY DESIGN: Systematic review and meta-analysis. OBJECTIVES: Indications for surgical decompression of gunshot wounds to the lumbosacral spine are controversial and based on limited data. METHODS: A systematic review of literature was conducted to identify studies that directly compare neurologic outcomes following operative and non-operative management of gunshot wounds to the lumbosacral spine. Studies were evaluated for degree of neurologic improvement, complications, and antibiotic usage. An odds ratio and 95% confidence interval were calculated for dichotomous outcomes which were then pooled by random-effects model meta-analysis. RESULTS: Five studies were included that met inclusion criteria. The total rate of neurologic improvement was 72.3% following surgical intervention and 61.7% following non-operative intervention. A random-effects model meta-analysis was carried out which failed to show a statistically significant difference in the rate of neurologic improvement between surgical and non-operative intervention (OR 1.07; 95% CI 0.45, 2.53; P = 0.88). In civilian only studies, a random-effects model meta-analysis failed to show a statistically significant difference in the rate of neurologic improvement between surgical and non-operative intervention (OR 0.75; 95% CI 0.21, 2.72; P = 0.66). Meta-analysis further failed to show a statistically significant difference in the rate of neurologic improvement between patients with either complete (OR 4.13; 95% CI 0.55, 30.80; P = 0.17) or incomplete (OR 0.38; 95% CI 0.10, 1.52; P = 0.17) neurologic injuries who underwent surgical and non-operative intervention. There were no significant differences in the number of infections and other complications between patients who underwent surgical and non-operative intervention. CONCLUSIONS: There were no statistically significant differences in the rate of neurologic improvement between those who underwent surgical or non-operative intervention. Further research is necessary to determine if surgical intervention for gunshot wounds to the lumbosacral spine, including in the case of retained bullet within the spinal canal, is efficacious. SAGE Publications 2021-07-19 2022-07 /pmc/articles/PMC9210234/ /pubmed/34275384 http://dx.doi.org/10.1177/21925682211030873 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by-nc-nd/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 License (https://creativecommons.org/licenses/by-nc-nd/4.0/) which permits non-commercial use, reproduction and distribution of the work as published without adaptation or alteration, without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Review Articles
Platt, Andrew
Dafrawy, Mostafa H. El
Lee, Michael J.
Herman, Martin H.
Ramos, Edwin
Gunshot Wounds to the Lumbosacral Spine: Systematic Review and Meta-Analysis
title Gunshot Wounds to the Lumbosacral Spine: Systematic Review and Meta-Analysis
title_full Gunshot Wounds to the Lumbosacral Spine: Systematic Review and Meta-Analysis
title_fullStr Gunshot Wounds to the Lumbosacral Spine: Systematic Review and Meta-Analysis
title_full_unstemmed Gunshot Wounds to the Lumbosacral Spine: Systematic Review and Meta-Analysis
title_short Gunshot Wounds to the Lumbosacral Spine: Systematic Review and Meta-Analysis
title_sort gunshot wounds to the lumbosacral spine: systematic review and meta-analysis
topic Review Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9210234/
https://www.ncbi.nlm.nih.gov/pubmed/34275384
http://dx.doi.org/10.1177/21925682211030873
work_keys_str_mv AT plattandrew gunshotwoundstothelumbosacralspinesystematicreviewandmetaanalysis
AT dafrawymostafahel gunshotwoundstothelumbosacralspinesystematicreviewandmetaanalysis
AT leemichaelj gunshotwoundstothelumbosacralspinesystematicreviewandmetaanalysis
AT hermanmartinh gunshotwoundstothelumbosacralspinesystematicreviewandmetaanalysis
AT ramosedwin gunshotwoundstothelumbosacralspinesystematicreviewandmetaanalysis