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Gunshot Wounds to the Lumbosacral Spine: Systematic Review and Meta-Analysis
STUDY DESIGN: Systematic review and meta-analysis. OBJECTIVES: Indications for surgical decompression of gunshot wounds to the lumbosacral spine are controversial and based on limited data. METHODS: A systematic review of literature was conducted to identify studies that directly compare neurologic...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9210234/ https://www.ncbi.nlm.nih.gov/pubmed/34275384 http://dx.doi.org/10.1177/21925682211030873 |
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author | Platt, Andrew Dafrawy, Mostafa H. El Lee, Michael J. Herman, Martin H. Ramos, Edwin |
author_facet | Platt, Andrew Dafrawy, Mostafa H. El Lee, Michael J. Herman, Martin H. Ramos, Edwin |
author_sort | Platt, Andrew |
collection | PubMed |
description | STUDY DESIGN: Systematic review and meta-analysis. OBJECTIVES: Indications for surgical decompression of gunshot wounds to the lumbosacral spine are controversial and based on limited data. METHODS: A systematic review of literature was conducted to identify studies that directly compare neurologic outcomes following operative and non-operative management of gunshot wounds to the lumbosacral spine. Studies were evaluated for degree of neurologic improvement, complications, and antibiotic usage. An odds ratio and 95% confidence interval were calculated for dichotomous outcomes which were then pooled by random-effects model meta-analysis. RESULTS: Five studies were included that met inclusion criteria. The total rate of neurologic improvement was 72.3% following surgical intervention and 61.7% following non-operative intervention. A random-effects model meta-analysis was carried out which failed to show a statistically significant difference in the rate of neurologic improvement between surgical and non-operative intervention (OR 1.07; 95% CI 0.45, 2.53; P = 0.88). In civilian only studies, a random-effects model meta-analysis failed to show a statistically significant difference in the rate of neurologic improvement between surgical and non-operative intervention (OR 0.75; 95% CI 0.21, 2.72; P = 0.66). Meta-analysis further failed to show a statistically significant difference in the rate of neurologic improvement between patients with either complete (OR 4.13; 95% CI 0.55, 30.80; P = 0.17) or incomplete (OR 0.38; 95% CI 0.10, 1.52; P = 0.17) neurologic injuries who underwent surgical and non-operative intervention. There were no significant differences in the number of infections and other complications between patients who underwent surgical and non-operative intervention. CONCLUSIONS: There were no statistically significant differences in the rate of neurologic improvement between those who underwent surgical or non-operative intervention. Further research is necessary to determine if surgical intervention for gunshot wounds to the lumbosacral spine, including in the case of retained bullet within the spinal canal, is efficacious. |
format | Online Article Text |
id | pubmed-9210234 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-92102342022-06-22 Gunshot Wounds to the Lumbosacral Spine: Systematic Review and Meta-Analysis Platt, Andrew Dafrawy, Mostafa H. El Lee, Michael J. Herman, Martin H. Ramos, Edwin Global Spine J Review Articles STUDY DESIGN: Systematic review and meta-analysis. OBJECTIVES: Indications for surgical decompression of gunshot wounds to the lumbosacral spine are controversial and based on limited data. METHODS: A systematic review of literature was conducted to identify studies that directly compare neurologic outcomes following operative and non-operative management of gunshot wounds to the lumbosacral spine. Studies were evaluated for degree of neurologic improvement, complications, and antibiotic usage. An odds ratio and 95% confidence interval were calculated for dichotomous outcomes which were then pooled by random-effects model meta-analysis. RESULTS: Five studies were included that met inclusion criteria. The total rate of neurologic improvement was 72.3% following surgical intervention and 61.7% following non-operative intervention. A random-effects model meta-analysis was carried out which failed to show a statistically significant difference in the rate of neurologic improvement between surgical and non-operative intervention (OR 1.07; 95% CI 0.45, 2.53; P = 0.88). In civilian only studies, a random-effects model meta-analysis failed to show a statistically significant difference in the rate of neurologic improvement between surgical and non-operative intervention (OR 0.75; 95% CI 0.21, 2.72; P = 0.66). Meta-analysis further failed to show a statistically significant difference in the rate of neurologic improvement between patients with either complete (OR 4.13; 95% CI 0.55, 30.80; P = 0.17) or incomplete (OR 0.38; 95% CI 0.10, 1.52; P = 0.17) neurologic injuries who underwent surgical and non-operative intervention. There were no significant differences in the number of infections and other complications between patients who underwent surgical and non-operative intervention. CONCLUSIONS: There were no statistically significant differences in the rate of neurologic improvement between those who underwent surgical or non-operative intervention. Further research is necessary to determine if surgical intervention for gunshot wounds to the lumbosacral spine, including in the case of retained bullet within the spinal canal, is efficacious. SAGE Publications 2021-07-19 2022-07 /pmc/articles/PMC9210234/ /pubmed/34275384 http://dx.doi.org/10.1177/21925682211030873 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by-nc-nd/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 License (https://creativecommons.org/licenses/by-nc-nd/4.0/) which permits non-commercial use, reproduction and distribution of the work as published without adaptation or alteration, without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Review Articles Platt, Andrew Dafrawy, Mostafa H. El Lee, Michael J. Herman, Martin H. Ramos, Edwin Gunshot Wounds to the Lumbosacral Spine: Systematic Review and Meta-Analysis |
title | Gunshot Wounds to the Lumbosacral Spine: Systematic Review and Meta-Analysis |
title_full | Gunshot Wounds to the Lumbosacral Spine: Systematic Review and Meta-Analysis |
title_fullStr | Gunshot Wounds to the Lumbosacral Spine: Systematic Review and Meta-Analysis |
title_full_unstemmed | Gunshot Wounds to the Lumbosacral Spine: Systematic Review and Meta-Analysis |
title_short | Gunshot Wounds to the Lumbosacral Spine: Systematic Review and Meta-Analysis |
title_sort | gunshot wounds to the lumbosacral spine: systematic review and meta-analysis |
topic | Review Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9210234/ https://www.ncbi.nlm.nih.gov/pubmed/34275384 http://dx.doi.org/10.1177/21925682211030873 |
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