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Disability, Health-Related Quality of Life and Mortality in Lumbar Spine Fusion Patients—A 5-Year Follow-Up and Comparison With a Population Sample

STUDY DESIGN: Prospective follow-up study. OBJECTIVES: We aimed to assess the effect of lumbar spine fusion (LSF) on disability, health-related quality of life and mortality in a 5-year follow-up, and to compare these results with the general population. METHODS: 523 consecutive LSF operations were...

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Autores principales: Toivonen, Leevi, Pekkanen, Liisa, Neva, Marko H., Kautiainen, Hannu, Kyrölä, Kati, Marttinen, Ilkka, Häkkinen, Arja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9210235/
https://www.ncbi.nlm.nih.gov/pubmed/33203243
http://dx.doi.org/10.1177/2192568220972977
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author Toivonen, Leevi
Pekkanen, Liisa
Neva, Marko H.
Kautiainen, Hannu
Kyrölä, Kati
Marttinen, Ilkka
Häkkinen, Arja
author_facet Toivonen, Leevi
Pekkanen, Liisa
Neva, Marko H.
Kautiainen, Hannu
Kyrölä, Kati
Marttinen, Ilkka
Häkkinen, Arja
author_sort Toivonen, Leevi
collection PubMed
description STUDY DESIGN: Prospective follow-up study. OBJECTIVES: We aimed to assess the effect of lumbar spine fusion (LSF) on disability, health-related quality of life and mortality in a 5-year follow-up, and to compare these results with the general population. METHODS: 523 consecutive LSF operations were included in a prospective follow-up. Disability was assessed by the Oswestry Disability Index (ODI), and HRQoL by the 36-item Short Form (SF-36) questionnaire using the physical and mental summary scores (PCS and MCS). The patients were compared with an age-, sex-, and residential area matched general population cohort. RESULTS: The preoperative ODI in the patients was 46 (SD 16), and the change at 5 years was −26 (95% CI: −24 to −28), p < 0.001. In the population, ODI (baseline 13, SD 16) remained unchanged. The preoperative PCS in the patients was 27 (SD 7), in the population 45 (SD 11), and the increase in the patients at 5 years was 8 (95% CI: 7 to 9), p < 0.001. The patients did not reach the population in ODI or PCS. The baseline MCS in the patients was 47 (SD 13), and the change at 5 years 4 (95% CI: 3 to 7), p < 0.001. MCS of the females reached the population at 5-year follow-up. When analyzing short and long fusions separately, comparable changes were seen in both subgroups. There was no difference in mortality between the patients (3.4%) and the population (4.8%), hazard ratio (HR) 0.86. CONCLUSIONS: Although the patients who had undergone LSF benefited from surgery still at 5 years, they never reached the physical level of the population.
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spelling pubmed-92102352022-06-22 Disability, Health-Related Quality of Life and Mortality in Lumbar Spine Fusion Patients—A 5-Year Follow-Up and Comparison With a Population Sample Toivonen, Leevi Pekkanen, Liisa Neva, Marko H. Kautiainen, Hannu Kyrölä, Kati Marttinen, Ilkka Häkkinen, Arja Global Spine J Original Articles STUDY DESIGN: Prospective follow-up study. OBJECTIVES: We aimed to assess the effect of lumbar spine fusion (LSF) on disability, health-related quality of life and mortality in a 5-year follow-up, and to compare these results with the general population. METHODS: 523 consecutive LSF operations were included in a prospective follow-up. Disability was assessed by the Oswestry Disability Index (ODI), and HRQoL by the 36-item Short Form (SF-36) questionnaire using the physical and mental summary scores (PCS and MCS). The patients were compared with an age-, sex-, and residential area matched general population cohort. RESULTS: The preoperative ODI in the patients was 46 (SD 16), and the change at 5 years was −26 (95% CI: −24 to −28), p < 0.001. In the population, ODI (baseline 13, SD 16) remained unchanged. The preoperative PCS in the patients was 27 (SD 7), in the population 45 (SD 11), and the increase in the patients at 5 years was 8 (95% CI: 7 to 9), p < 0.001. The patients did not reach the population in ODI or PCS. The baseline MCS in the patients was 47 (SD 13), and the change at 5 years 4 (95% CI: 3 to 7), p < 0.001. MCS of the females reached the population at 5-year follow-up. When analyzing short and long fusions separately, comparable changes were seen in both subgroups. There was no difference in mortality between the patients (3.4%) and the population (4.8%), hazard ratio (HR) 0.86. CONCLUSIONS: Although the patients who had undergone LSF benefited from surgery still at 5 years, they never reached the physical level of the population. SAGE Publications 2020-11-18 2022-07 /pmc/articles/PMC9210235/ /pubmed/33203243 http://dx.doi.org/10.1177/2192568220972977 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by-nc-nd/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 License (https://creativecommons.org/licenses/by-nc-nd/4.0/) which permits non-commercial use, reproduction and distribution of the work as published without adaptation or alteration, without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Original Articles
Toivonen, Leevi
Pekkanen, Liisa
Neva, Marko H.
Kautiainen, Hannu
Kyrölä, Kati
Marttinen, Ilkka
Häkkinen, Arja
Disability, Health-Related Quality of Life and Mortality in Lumbar Spine Fusion Patients—A 5-Year Follow-Up and Comparison With a Population Sample
title Disability, Health-Related Quality of Life and Mortality in Lumbar Spine Fusion Patients—A 5-Year Follow-Up and Comparison With a Population Sample
title_full Disability, Health-Related Quality of Life and Mortality in Lumbar Spine Fusion Patients—A 5-Year Follow-Up and Comparison With a Population Sample
title_fullStr Disability, Health-Related Quality of Life and Mortality in Lumbar Spine Fusion Patients—A 5-Year Follow-Up and Comparison With a Population Sample
title_full_unstemmed Disability, Health-Related Quality of Life and Mortality in Lumbar Spine Fusion Patients—A 5-Year Follow-Up and Comparison With a Population Sample
title_short Disability, Health-Related Quality of Life and Mortality in Lumbar Spine Fusion Patients—A 5-Year Follow-Up and Comparison With a Population Sample
title_sort disability, health-related quality of life and mortality in lumbar spine fusion patients—a 5-year follow-up and comparison with a population sample
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9210235/
https://www.ncbi.nlm.nih.gov/pubmed/33203243
http://dx.doi.org/10.1177/2192568220972977
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