Acute sleep deprivation upregulates serotonin 2A receptors in the frontal cortex of mice via the immediate early gene Egr3

Serotonin 2A receptors (5-HT(2A)Rs) mediate the hallucinogenic effects of psychedelic drugs and are a key target of the leading class of medications used to treat psychotic disorders. These findings suggest that dysfunction of 5-HT(2A)Rs may contribute to the symptoms of schizophrenia, a mental illn...

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Detalles Bibliográficos
Autores principales: Zhao, Xiuli, Ozols, Annika B., Meyers, Kimberly T., Campbell, Janet, McBride, Andrew, Marballi, Ketan K., Maple, Amanda M., Raskin, Carren, Mishra, Abhinav, Noss, Serena M., Beck, Kelsey L., Khoshaba, Rami, Bhaskara, Amulya, Godbole, Meghna N., Lish, James R., Kang, Paul, Hu, Chengcheng, Palner, Mikael, Overgaard, Agnete, Knudsen, Gitte M., Gallitano, Amelia L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9210263/
https://www.ncbi.nlm.nih.gov/pubmed/35001075
http://dx.doi.org/10.1038/s41380-021-01390-w

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