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RNA sequencing-based screen for reactivation of silenced alleles of autosomal genes

In mammalian cells, maternal and paternal alleles usually have similar transcriptional activity. Epigenetic mechanisms such as X-chromosome inactivation (XCI) and imprinting were historically viewed as rare exceptions to this rule. Discovery of autosomal monoallelic autosomal expression (MAE) a deca...

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Detalles Bibliográficos
Autores principales:	Gupta, Saumya, Lafontaine, Denis L, Vigneau, Sebastien, Mendelevich, Asia, Vinogradova, Svetlana, Igarashi, Kyomi J, Bortvin, Andrew, Alves-Pereira, Clara F, Nag, Anwesha, Gimelbrant, Alexander A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9210281/ https://www.ncbi.nlm.nih.gov/pubmed/35100361 http://dx.doi.org/10.1093/g3journal/jkab428

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