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Ankfn1-mutant vestibular defects require loss of both ancestral and derived paralogs for penetrance in zebrafish

How and to what degree gene duplication events create regulatory innovation, redundancy, or neofunctionalization remain important questions in animal evolution and comparative genetics. Ankfn1 genes are single copy in most invertebrates, partially duplicated in jawed vertebrates, and only the derive...

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Detalles Bibliográficos
Autores principales: Ross, Kevin D, Ren, Jie, Zhang, Ruilin, Chi, Neil C, Hamilton, Bruce A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9210315/
https://www.ncbi.nlm.nih.gov/pubmed/35100349
http://dx.doi.org/10.1093/g3journal/jkab446