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Effects of amyloid-β on protein SUMOylation and levels of mitochondrial proteins in primary cortical neurons

Defining the molecular changes that underlie Alzheimer’s disease (AD) is an important question in neuroscience. Here, we examined changes in protein SUMOylation, and proteins involved in mitochondrial dynamics, in an in vitro model of AD induced by application of amyloid-β 1–42 (Aβ(1–42)) to culture...

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Detalles Bibliográficos
Autores principales: Soares, Ericks S., de Souza, Ana C. Guerra, Zanella, Camila A., Carmichael, Ruth E., Henley, Jeremy M., Wilkinson, Kevin A., Cimarosti, Helena I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9210492/
https://www.ncbi.nlm.nih.gov/pubmed/35746977
http://dx.doi.org/10.1016/j.ibneur.2022.01.003