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Effects of amyloid-β on protein SUMOylation and levels of mitochondrial proteins in primary cortical neurons
Defining the molecular changes that underlie Alzheimer’s disease (AD) is an important question in neuroscience. Here, we examined changes in protein SUMOylation, and proteins involved in mitochondrial dynamics, in an in vitro model of AD induced by application of amyloid-β 1–42 (Aβ(1–42)) to culture...
Autores principales: | Soares, Ericks S., de Souza, Ana C. Guerra, Zanella, Camila A., Carmichael, Ruth E., Henley, Jeremy M., Wilkinson, Kevin A., Cimarosti, Helena I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9210492/ https://www.ncbi.nlm.nih.gov/pubmed/35746977 http://dx.doi.org/10.1016/j.ibneur.2022.01.003 |
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