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NLRP3 inflammasome-mediated choroid plexus hypersecretion contributes to hydrocephalus after intraventricular hemorrhage via phosphorylated NKCC1 channels

BACKGROUND: Hydrocephalus is a severe complication of intracerebral hemorrhage with ventricular extension (ICH-IVH) and causes cerebrospinal fluid (CSF) accumulation. The choroid plexus epithelium plays an important role in CSF secretion and constitutes the blood–CSF barrier within the brain–immune...

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Detalles Bibliográficos
Autores principales: Zhang, Zhaoqi, Tan, Qiang, Guo, Peiwen, Huang, Suna, Jia, Zhengcai, Liu, Xin, Feng, Hua, Chen, Yujie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9210649/
https://www.ncbi.nlm.nih.gov/pubmed/35729645
http://dx.doi.org/10.1186/s12974-022-02530-x

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