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Myeloid DNA methyltransferase3b deficiency aggravates pulmonary fibrosis by enhancing profibrotic macrophage activation

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive and severe disease characterized by excessive matrix deposition in the lungs. Macrophages play crucial roles in maintaining lung homeostasis but are also central in the pathogenesis of lung diseases like pulmonary fibrosis. Es...

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Detalles Bibliográficos
Autores principales:	Qin, Wanhai, Spek, C. Arnold, Scicluna, Brendon P., van der Poll, Tom, Duitman, JanWillem
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9210707/ https://www.ncbi.nlm.nih.gov/pubmed/35725453 http://dx.doi.org/10.1186/s12931-022-02088-5

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