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Blocking TIGIT/CD155 signalling reverses CD8(+) T cell exhaustion and enhances the antitumor activity in cervical cancer

OBJECTIVE: TIGIT/CD155 has attracted widespread attention as a new immune checkpoint and a potential target for cancer immunotherapy. In our study, we evaluated the role of TIGIT/CD155 checkpoints in the progression of cervical cancer. METHODS: The expression of CD155 and TIGIT in cervical cancer ti...

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Detalles Bibliográficos
Autores principales:	Liu, Lu, Wang, Aihong, Liu, Xiaoli, Han, Sai, Sun, Yu, Zhang, Junhua, Guo, Lingyu, Zhang, Youzhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9210727/ https://www.ncbi.nlm.nih.gov/pubmed/35729552 http://dx.doi.org/10.1186/s12967-022-03480-x

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